The main aim of this work was to develop a time-saving and cost-effective purification
method of infectious plant viral nanoparticles. Virions of Tomato bushy stunt virus
(TBSV), which is a member of Tombusvirus genus, ...
Neutrophils, migrating to the site of infection, are able to release serine proteases after being activated. These serine proteases comprise cathepsin G (CatG), neutrophil elastase protease 3 (PR3), and neutrophil serine ...
Algal blooms occur in freshwater bodies throughout the world, often leading to fish
kills. Cases of these kills along the Ural River were reported in 2018–2019, involving
significant amount of sturgeon in fish farming ...
One of the major causes of a drastically shorter life expectancy and one of the most prevalent
diseases in the world today is cancer. Given the data on the rise in cancer cases throughout the
world, it is obvious that, ...
Rheumatoid arthritis (RA) is a chronic autoimmune disease causing inflammation of joints, cartilage destruction and bone erosion. Biomarkers and new drug targets are actively sought and progressed to improve available ...
Myngbay, Askhat; Manarbek, Limara; Ludbrook, Steve; Kunz, Jeannette(International Journal o f Molecular Sciences, 2021-02-28)
Rheumatoid arthritis (RA) is a chronic autoimmune disease causing inflammation of joints, cartilage destruction and bone erosion. Biomarkers and new drug targets are actively sought and progressed to improve available ...
Serine proteases neutrophil elastase (NE), protease 3 (PR3), cathepsin G (CatG), and neutrophil serine protease 4 (NSP4) are released by activated neutrophils swarming around the place of pathogen invasion to provoke an ...
Kazakhstan covers a vast territory, and it has always been a land of nomadic pastoralism, where domesticated horses and sheep were moved by nomadic people across the steppe. Previous reports suggest that sheep breeds from ...
Background: HIV outbreaks in the Former Soviet Union (FSU) countries were characterized by repeated transmission of the HIV variant AFSU, which is now classified as a distinct subtype A sub-subtype called A6. The current ...
David, Michael Shola; Kanayeva, Damira(Frontiers in Cellular and Infection Microbiology, 2022-09-29)
The exponential spread of COVID-19 has prompted the need to develop
a simple and sensitive diagnostic tool. Aptamer-based detection assays like
ELONA are promising since they are inexpensive and sensitive. Aptamers ...
Meirkhanova, Ayagoz(Nazarbayev University School of Sciences and Humanities, 2022)
Increasing evidence reports adverse effects of climate change on freshwater ecosystems
and harmful algal blooms in particular, but response mechanisms of such heterogeneous
communities are poorly understood. Environmental ...
Zhumabekova, Zhazira(Nazarbayev University School of Sciences and Humanities, 2022-06)
Carcinoembryonic antigen (CEA) is an important Food and Drug Administration
approved biomarker in cancer detection, especially in colorectal cancer. This research is
based on the development of a real-time rapid detection ...
Shola David, Michael(Nazarbayev University School of Sciences and Humanities, 2022-06)
The rapid spread of COVID’19 has necessitated the need for the development of rapid diagnostic
techniques as a strategy to contain further transmission of the virus. Aptamer-based detection assay
like enzyme-linked ...
Introduction: Coagulation parameters are important determinants for COVID-19 infection. We conducted meta-analysis to assess the association between early hemostatic parameters and infection severity.
Methods: Electronic ...
Kulseiit, Dana(Nazarbayev University School of Sciences and Humanities, 2022-06)
Cancer is one of the leading causes of deaths worldwide accounting for 10 million people deceases in 2020. Metastatic spreading is the key feature that makes cancer difficult to cure. Stiffness and adhesion of cancer cells ...
Glioblastoma represents the most aggressive tumor of the central nervous system. Due to invasion of glioblastoma
stem cells into the healthy tissue, chemoresistance, and recurrence of the tumor, it is difficult to ...
The serine proteases neutrophil elastase (NE), proteinase 3 (PR3), cathepsin G (CatG),
and neutrophil serine protease 4 (NSP4) are secreted by activated neutrophils as a part of
the innate immune response against invading ...
Kazybay, Bexultan; Ahmad, Ashfaq; Xie, Yingqiu(Travel Medicine and Infectious Disease, 2022)
Given that international and domestic flights now require only adults
to be vaccinated or have negative PCR test results, adolescents’ vacci nation of COVID-19 for safe travel needs urgent consideration. As adults
benefit ...
Coronavirus disease 2019 (COVID-19) can lead to multi-organ failure influenced by co morbidities and age. Binding of the severe acute respiratory syndrome coronavirus 2 spike protein
(SARS-CoV-2 S protein) to angiotensi ...
More than six billion tests for COVID-19 has been already performed in the world. The testing for SARS-CoV-2
(Severe Acute Respiratory Syndrome Coronavirus-2) virus and corresponding human antibodies is essential not ...