THE FREQUENT SAMPLING OF WOUND SCRATCH ASSAY REVEALS THE “OPPORTUNITY” WINDOW FOR QUANTITATIVE EVALUATION OF CELL MOTILITY-IMPEDING DRUGS

Kauanova, Sholpan; Urazbayev, Arshat; Vorobjev, Ivan

dc.contributor.author	Kauanova, Sholpan
dc.contributor.author	Urazbayev, Arshat
dc.contributor.author	Vorobjev, Ivan
dc.date.accessioned	2021-10-06T17:30:09Z
dc.date.available	2021-10-06T17:30:09Z
dc.date.issued	2021-03-11
dc.identifier.citation	Kauanova S, Urazbayev A and Vorobjev I (2021) The Frequent Sampling of Wound Scratch Assay Reveals the “Opportunity” Window for Quantitative Evaluation of Cell Motility-Impeding Drugs. Front. Cell Dev. Biol. 9:640972. doi: 10.3389/fcell.2021.640972	en_US
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/5858
dc.description.abstract	Wound healing assay performed with automated microscopy is widely used in drug testing, cancer cell analysis, and similar approaches. It is easy to perform, and the results are reproducible. However, it is usually used as a semi-quantitative approach because of inefficient image segmentation in transmitted light microscopy. Recently, several algorithms for wound healing quantification were suggested, but none of them was tested on a large dataset...	en_US
dc.language.iso	en	en_US
dc.publisher	Front. Cell Dev. Biol.	en_US
dc.rights	Attribution-NonCommercial-ShareAlike 3.0 United States	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/3.0/us/	*
dc.subject	wound healing	en_US
dc.subject	high-throughput	en_US
dc.subject	label-free microscopy	en_US
dc.subject	live-cell imaging	en_US
dc.subject	segmentation automation	en_US
dc.subject	cell motility	en_US
dc.title	THE FREQUENT SAMPLING OF WOUND SCRATCH ASSAY REVEALS THE “OPPORTUNITY” WINDOW FOR QUANTITATIVE EVALUATION OF CELL MOTILITY-IMPEDING DRUGS	en_US
dc.type	Article	en_US
workflow.import.source	science