Browsing Research Institute of Bioengineering, Regenerative Medicine and Neurophysiology by Author "24f713c7-d9d1-4e77-82b0-275da8d6f27c"

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MESENCHYMAL STEM CELLS COATED WITH SYNTHETIC BONE-TARGETING POLYMERS ENHANCE OSTEOPOROTIC BONE FRACTURE REGENERATION

Safarova, Yuliya; Olzhayev, Farkhad; Umbayev, Bauyrzhan; Tsoy, Andrey; Hortelano, Gonzalo; Tokay, Tursonjan; Murata, Hironobu; Russell, Alan; Askarova, Sholpan (MDPI AG, 2020-10-12)

Osteoporosis is a progressive skeletal disease characterized by reduced bone density leading to bone fragility and an elevated risk of bone fractures. In osteoporotic conditions, decrease in bone density happens due to the ...
Mesenchymal stem cells modifications for enhanced bone targeting and bone regeneration

Safarova, Yuliya; Umbayev, Bauyrzhan; Hortelano, Gonzalo; Askarova, Sholpan (Future Medicine, 2020-04-16)

In pathological bone conditions (e.g., osteoporotic fractures or critical size bone defects), increasing the pool of osteoblast progenitor cells is a promising therapeutic approach to facilitate bone healing. Since mesenchymal ...