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02.National Laboratory Astana

02.National Laboratory Astana

 

Private institution «NATIONAL LABORATORY ASTANА» Nazarbayev University includes Center for Life Sciences and Center for Energy and Advanced Materials Science. The main goals of the institution is carrying out multidisciplinary basic and/or applied research in the field of life sciences, energy, and other interdisciplinary areas of science, as well as activities to establish a scientific laboratory, experimental bases, centers, institutes for the development and implementation of scientific, scientific and technical, educational programs and training.

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  • Kushugulova, Almagul R.; Löber, Ulrike; Akpanova, Saniya; Rysbekov, Kairat; Kozhakhmetov, Samat S.; Khassenbekova, Zhanagul R.; Essex, Morgan; Nurgozhina, Ayaulym; Nurgaziyev, Madiyar; Babenko, Dmitriy; Marko, Lajos; Forslund, Sofia K. (Frontiers Media S.A., 2021-04-21)
    Introduction: Probiotics and prebiotics are widely used for recovery of the human gut microbiome after antibiotic treatment. High antibiotic usage is especially common in children with developing microbiome. We hypothesized ...
  • Karabayev, Daniyar; Molkenov, Askhat; Yerulanuly, Kaiyrgali; Kabimoldayev, Ilyas; Daniyarov, Asset; Sharip, Aigul; Seisenova, Ainur; Zhumadilov, Zhaxybay; Kairov, Ulykbek (PeerJ Inc., 2021-05-03)
    Background. High-throughput sequencing platforms generate a massive amount of high-dimensional genomic datasets that are available for analysis. Modern and user-friendly bioinformatics tools for analysis and interpretation ...
  • Baiken, Yeldar; Kanayeva, Damira; Taipakova, Sabira; Groisman, Regina; Ishchenko, Alexander A.; Begimbetova, Dinara; Matkarimov, Bakhyt; Saparbaev, Murat (Frontiers in Cell and Developmental Biology, 2021-01-22)
    Chemical alterations in DNA induced by genotoxic factors can have a complex nature such as bulky DNA adducts, interstrand DNA cross-links (ICLs), and clustered DNA lesions (including double-strand breaks, DSB). Complex DNA ...
  • Zholdybayeva, Elena V.; Kozhahmetova, Saniya; Tarlykov, Pavel; Atavliyeva, Sabina; Mukhtarova, Kymbat; Syzdykov, Tleuli; Khasenov, Ruslan; Shevtsov, Alexsandr; Amirgazin, Asylulan; Daniyarov, Asset; Ramankulov, Yerlan (Microbiology Resource Announcements, 2021-02-04)
    Our aim was to study the nucleotide sequences of 9 previously undescribed strains of B. fragilis collected from patients with intra-abdominal diseases at city hospitals in Nur-Sultan, Kazakhstan.
  • Erper, Ismail; Ozer, Goksel; Kalendar, Ruslan; Avci, Sirin; Yildirim, Elif; Alkan, Mehtap; Turkkan, Muharrem (Journal of Fungi, 2021-03-21)
    A total of 132 Rhizoctonia isolates were recovered from red cabbage plants with root rot and wirestem symptoms in the province of Samsun (Turkey) between 2018 and 2019. Based on the sequence analysis of the internal ...
  • Zhylkaidarova, Alma; Kaidarova, Dilyara; Batyrbekov, Kanat; Shatkovskaya, Oxana; Begimbetova, Dinara (Clinical Endoscopy, 2020-05-25)
    We carried out an analysis of the total incidence of colon cancer throughout Kazakhstan. Retrospectively, according to the regional reports on endoscopic screening, the study showed an increase in the age-related incidence ...
  • Nurpeissova, Arailym; Adi, Akylbek; Aishova, Assylzat; Mukanova, Aliya; Kim, Sung-Soo; Bakenov, Zhumabay (Materials Today Energy, 2020-06)
    A three-dimensional (3D) architecture design of the battery electrodes is believed to enhance the energy and power densities of conventional lithium-ion batteries. In this paper, we report a unique 3D architecture anode ...
  • Zhylkaidarova, Alma; Kaidarova, Dilyara; Batyrbekov, Kanat; Shatkovskaya, Oxana; Begimbetova, Dinara (Clinical Endoscopy, 2020-05)
    Colorectal cancer (CRC) is one of the global health problems and is the third leading cause of morbidity and second leading cause of mortality from cancer worldwide [1,2]. In the United States and European countries, the ...
  • Kudaibergenova, R.M.; Nurlybayeva, А.N.; Kantarbayeva, S.M.; Matniyazova, G.К.; Baibazarova, Е.; Sugurbekova, G.K. (Series chemistry and technology, 2020)
    The article is devoted to the unique material graphene (carbon modification), discovered in 2004 by immigrants from Russia Andrei Geim (Andre K. Geim) and Konstantin Novoselov (Konstantin Novoselov), who won the Nobel ...
  • Kalendar, Ruslan; Shustov, Alexandr V.; Schulman, Alan H. (Frontiers Media S.A., 2021-06-22)
    Genome walking (GW), a strategy for capturing previously unsequenced DNA fragments that are in proximity to a known sequence tag, is currently predominantly based on PCR. Recently developed PCR-based methods allow for ...
  • Kozhakhmetov, Samat S.; Babenko, Dmitriy; Kozhakhmetova, Saniya; Tuyakova, Altynay; Nurgaziyev, Madiyar; Nurgozhina, Ayaulym; Muhanbetganov, Nurislam; Chulenbayeva, Laura; Sergazy, Shynggys; Gulyayev, Alexander; Tanabayev, Baimakhan; Saliev, Timur; Kushugulova, Almagul R. (Elsevier Ltd, 2021-06-08)
    Inflammatory bowel disease is one of the serious burdens of clinical medicine and healthcare. This study investigated the potential of a biological product based on mare's milk and metabolites of symbiotic microflora for ...
  • Norem, J.; Insepov, Z.; Hassanein, A. (Nature Research, 2021-01-27)
    Although used in the design and costing of large projects such as linear colliders and fusion tokamaks, the theory of vacuum arcs and gradient limits is not well understood. Almost 120 years after the isolation of vacuum ...
  • Kairov, Ulykbek; Molkenov, Askhat; Rakhimova, Saule; Kozhamkulov, Ulan; Sharip, Aigul; Karabayev, Daniyar; Daniyarov, Asset; Lee, Joseph H.; Terwilliger, Joseph D.; Akilzhanova, Ainur; Zhumadilov, Zhaxybay (BioMed Central Ltd, 2021-02-04)
    Objectives: Kazakhstan is a Central Asian crossroad of European and Asian populations situated along the way of the Great Silk Way. The territory of Kazakhstan has historically been inhabited by nomadic tribes and today ...
  • Yessenkyzy, Assylzhan; Saliev, Timur; Zhanaliyeva, Marina; Masoud, Abdul-Razak; Umbayev, Bauyrzhan; Sergazy, Shynggys; Krivykh, Elena; Gulyayev, Alexander; Nurgozhin, Talgat (MDPI, 2020-05-08)
    It has been thought that caloric restriction favors longevity and healthy aging where autophagy plays a vital role. However, autophagy decreases during aging and that can lead to the development of aging-associated diseases ...
  • Shabdan, Yerkin; Markhabayeva, Aiymkul; Bakranov, Nurlan; Nuraje, Nurxat (MDPI, 2020-09-18)
    This review focuses on tungsten oxide (WO3) and its nanocomposites as photoactive nanomaterials for photoelectrochemical cell (PEC) applications since it possesses exceptional properties such as photostability, high ...
  • Umbayev, Bauyrzhan; Askarova, Sholpan; Almabayeva, Aigul; Saliev, Timur; Masoud, Abdul-Razak; Bulanin, Denis (Hindawi, 2020-06-17)
    Skin aging has been associated with a higher dietary intake of carbohydrates, particularly glucose and galactose. In fact, the carbohydrates are capable of damaging the skin’s vital components through nonenzymatic glycation, ...
  • Ogay, Vyacheslav; Kumasheva, Venera; Li, Yelena; Mukhlis, Sholpan; Sekenova, Aliya; Olzhayev, Farkhad; Tsoy, Andrey; Umbayev, Baurzhan; Askarova, Sholpan; Shpekov, Azat; Kaliyev, Assylbek; Zhetpisbayev, Berik; Makhambetov, Yerbol; Akshulakov, Serik; Saparov, Arman; Ramankulov, Yerlan (SAGE Publications, 2020-09-04)
    Pericytes possess high multipotent features and cell plasticity, and produce angiogenic and neurotrophic factors that indicate their high regenerative potential. The aim of this study was to investigate whether transplantation ...
  • Nurpeissova, Arailym; Mukanova, Aliya; Kalimuldina, Gulnur; Umirov, Nurzhan; Kim, Sung-Soo; Bakenov, Zhumabay (Nanomaterials, 2020-10-10)
    Low dimensional Si-based materials are very promising anode candidates for the next-generation lithium-ion batteries. However, to satisfy the ever-increasing demand in more powerful energy storage devices, electrodes based ...
  • Kauanova, Sholpan; Urazbayev, Arshat; Vorobjev, Ivan (Frontiers Media, 2021-03)
    Wound healing assay performed with automated microscopy is widely used in drug testing, cancer cell analysis, and similar approaches. It is easy to perform, and the results are reproducible. However, it is usually used as ...
  • Khapilina, Oxana; Raiser, Olesya; Danilova, Alevtina; Shevtsov, Vladislav; Turzhanova, Ainur; Kalendar, Ruslan (PeerJ, 2021-01)
    Analysis of the genetic diversity of natural populations of threatened and endangered species of plants is a main aspect of conservation strategy. The endangered species Allium altaicum is a relict plant of the Ice Age and ...

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