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Transcriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiency

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dc.contributor.author Adarichev, V. A.
dc.contributor.author Sarkar, S.
dc.contributor.author Kalamov, N.
dc.contributor.author Brucker, J.
dc.contributor.author Forde, T. S.
dc.contributor.author Shekhani, M.T.
dc.contributor.author Lyons, B.
dc.date.accessioned 2015-10-28T09:55:50Z
dc.date.available 2015-10-28T09:55:50Z
dc.date.issued 2013
dc.identifier.uri http://nur.nu.edu.kz/handle/123456789/560
dc.description.abstract We found that Pgis2-congenic mice that carry genetically-deficient copy of C5(Hc) complement component were susceptible to collagen antibody-induced arthritis while inflammation was transient. Using differential gene expression analysis tools, we identified 20 genes whose down/up regulation in Pgis2-congenic mice might rescue C5 complement deficiency or, in a wider sense, rescue the function of the entire Pgis2 locus. ru_RU
dc.language.iso en ru_RU
dc.publisher Nazarbayev University ru_RU
dc.subject first research week ru_RU
dc.subject arthritis ru_RU
dc.subject science ru_RU
dc.title Transcriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiency ru_RU
dc.type Abstract ru_RU


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