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Browsing Abstracts by Title

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  • MOUSE CYTOKINE-INDUCED KILLER CELLS DEVELOPED FROM DIFFERENT SOURCES 
    Issabekova, A.; Zhunussova, M.; Zhumabekova, M.; Ogay, V. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: In Kazakhstan, death from colorectal cancer is on the leading position among cancer-related deaths in the population, and since 2013 colorectal cancer is one of the three cancer diseases subject to the ...
  • MRI-BASED STUDY OF VARIOUS COGNITIVE IMPAIRMENTS: CROSS-SECTIONAL STUDY 
    Kossumov, Alibek; Supiyev, Adil (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Clinical and diagnostic criteria for cognitive impairments are based neurophysiological tests or the presence of a history of vascular disease and stroke following the MRI scan. Materials and methods: The ...
  • MULTIDRUG-RESISTANT TUBERCULOSIS: WHOLE-GENOME SEQUENCING AND BIOINFORMATICS ANALYSIS 
    Kairov, U.; Kozhamkulov, U.; Daniyarov, A.; Molkenov, A.; Akhmetova, A.; Rakhimova, S.; Akilzhanova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction:Tuberculosis (TB) remains a serious public health threat worldwide. It is estimated that approximately one-third of the world’s population has been infected with multidrug-resistant tuberculosis (MDR-TB), ...
  • MULTIPLE SYSTEM ATROPHY, CEREBELLAR VARIANT: RARE CLINICAL CASE 
    Akhmetova, Zh.; Isilbaeva, A.; Ainabekova, B.; Kaisarbekova, A.; Meiramova, A.; Imanova, A.; Nabieva, F.; Hydyrpatsha, L. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Multisystem atrophy is a rare steadily progressing neurodegenerative disease, manifested by parkinsonism, cerebellar ataxia and autonomic failure. The cerebellar variant of multisystem atrophy is much less ...
  • MULTIPLEX LIGATION-DEPENDENT PROBE AMPLIFICATION OF MICRODELETION SYNDROMS 
    Uakhit, R.; Tolegen, N.; Bayanova, M. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Microdeletion syndromes are an extensive group of diseases affecting various organs and systems. These diseases are caused by deletions of small sections of chromosomes. Previously, most microdeletion ...
  • Mutation Analysis of the NRLP3 Gene in Children With Cryopyrin-Associated Fever 
    Auyeryanova, T.; Uakhit, R.; Assylbekova, M.; Mukusheva, Z.; Bayanova, M. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: CAPS is a group of severe multi-system, auto-inflammatory diseases with an autosomal dominant type of inheritance associated with mutations in the cryopyrin NLRP3 gene located on the first chromosome (1q44). ...
  • NEUROPROTECTIVE PROPERTIES OF PLANT EXTRACT FROM LIMONIUM GMELINII 
    Nurkenov, T.T.; Abzhanova, E.; Turgambayeva, A.; Zhusupova, G.E.; Shalakhmetova, T.M.; Tsoy, A.K.; Askarova, Sh.N. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    logic conditions. When excess ROS are present within the cell, this oxidative stress may have profound deleterious effects on the cell, including the direct oxidation of biomolecules (e.g., lipid, protein, and DNA), ...
  • Neurosensory Hearing Loss in Children With Bacterial Meningitis 
    Seidullayeva, A.; Bayasheva, D.; Turdalina, B.; Omarova, A.; Kozhakhmetov, S. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction. Bacterial meningitis (BM) is one of the causes of acquired neurosensory hearing loss in children.In patients undergoing BM, hearing loss is accompanied by ossification of the structural inner ear. Methods: ...
  • New Screening Options for Patients With Thalassemia: Lebanon Experience 
    Andrusha, A.B.; Mohamad, B.S. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Morbidity and mortality in beta thalassemia are caused by anemia and iron overload. The prognosis of patients with thalassemia major depends on the patient’s adherence to treatment programs. The early ...
  • NEW TREATMENT STRATEGY AGAINST ISCHEMIC BRAIN DAMAGE BASED ON COMBINED APPLICATION OF STEM CELL THERAPY AND PLANT POLYPHENOLS 
    Nurkenov, T.T.; Tsoy, A.K.; Zhusupova, G.E.; Olzhayev, F.S.; Ogay, V.B.; Umbayev, B.A.; Shalakhmetova, T.M.; Askarova, Sh.N. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: There is a number of data indicating that plant polyphenols can provide protection against neurodegenerative changes associated with cerebral ischemia. On the other hand, it has been shown that application ...
  • NUMERICAL AND EXPERIMENTAL ANALYSIS OF THE 3D PRINTED MULTI-MATERIAL ANKLE-FOOT ORTHOSIS 
    Otepbergenov, T.; Smagulov, Zh.; Kurokawa, S.; Ali, Md. Hazrat (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    The application of 3D printing in medicine is the major area to concern in the nearest future. Namely, it is convenient to additively manufacture the Ankle-Foot Orthosis (AFO) by fused-deposition modeling 3D printer. AFO ...
  • ORIGINAL METHODOLOGY OF ANNULOPLASTY OF THE MITRAL VALVE WITH A STABILIZED AUTOPERICARDIUM IN DEGENERATIVE HEART DISEASES 
    Zhurko, S.; Olzhayev, F.; Gamzaev, A.; Fedorov, S.; Pimenova, P. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: We have evaluated the results of using stabilized autopericardium for the correction of the mitral valve (MV) defects in patients with degenerative heart diseases. Methods: For the period from 2017-2019, ...
  • PHOTOSENSITIZING TIO2- POLYMERIC MICROPARTICLES FOR PHOTODYNAMIC THERAPY: EVALUATION OF ANTITUMOR EFFECT IN VITRO 
    Naren, A.; Turarova, G.; Akilbekova, D.; Koole, Levinus H. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: TiO2is a photocatalytic agent excited by ultraviolet (UV) light and upon the radiation it produces oxidizing radicals. TiO2is used in photodynamic therapy (PDT) for focal cancer treatment as well as post ...
  • POTASSIUM CHANNEL GENES KCNQ1, KCNE1/2, KCNH2 (HERG) MUTATIONS IN PATIENTS WITH ATRIAL FIBRILLATION IN KAZAKHSTAN 
    Abilova, Zhannur; Rakhimova, Saule; Akhmetova, Ainur; Zhalbinova, Madina; Nuralinov, Omirbek; Rashbayeva, Gulzhaina; Akilzhanova, Gulbanu; Abdrakhmanov, Ayan; Bekbosynova, Mahabbat; Akilzhanova, Ainur (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Background: Atrial fibrillation (AF) is a common arrhythmia of substantial public health importance, a major risk factor for stroke, heart failure, and other cardiovascular morbidities. Recent evidence demonstrates a ...
  • PREVALENCE OF MILD COGNITIVE IMPAIRMENT AMONG OLDER PEOPLE IN KAZAKHSTAN AND POTENTIAL RISK FACTORS 
    Tsoy, Radmila T.; Turuspekova, Saule T.; Klipitskaya, Nina K.; Mereke, Alibek; Cumming, Robert G. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Although there is a high prevalence of cognitive impairment among the old population of Kazakhstan, there is a lack of epidemiological research in this area. Assessment of mild cognitive impairment (MCI) as a transitional ...
  • RECENT PROGRESS IN TARGETED RADIOISOTOPE THERAPY (TRT) AT QST, JAPAN 
    Higashi, Tatsuya (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Targeted Radioisotope Therapy (TRT) is known as a radiotherapy using cytotoxic radioisotopes which are administered orally or intravenously in a patient and accumulate in a targeted organ or a tumor. Recently, QST started ...
  • RELATION OF ATHEROSCLEROSIS AND LIPID PROFILE INDICATORS 
    Ахметова, К.; Бенберин, В.; Вощенкова, Т.; Дробченко, Е.; Нагимтаева, А. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: The prevalence of cardiovascular disease (CVD) and its associated costs continue to increase. CVDs are known as the leading cause of death. This takes the life of 17.7 million people annually, which is 31% ...
  • RESULTS OF THE AUTOLOGOUS MESENCHYMAL STEM CELL TRANSPLANTATION IN PATIENTS WITH TYPE 1DIABETES MELLITUS 
    Ulyanova, O.; Baigenzhin, A.; Askarov, M.; Kozina, L.; Karibekov, T.; Taubaldieva, Zh.; Serebrennikova, D.; Boltanova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Type 1diabetes mellitus (T1DM) remains one of the main public healthcare problems worldwide with a tendency to steady growth. T1DM leads to kidney failure, blindness, heart attacks and strokes, which account ...
  • The Role of Markers of Acute Inflammatory Response in the Early Differential Diagnosis of Meningitis in Children 
    Ташенов, С.А.; Баешева, Д.А.; Сейдуллаева, А.Ж.; Нуртазина, Г.Г. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: The most common clinical option in the structure of enterovirus infection is serous meningitis, which accounts for up to 70% of all neuroinfections in children. Considering that at present, meningitis of ...
  • THE ROLE OF THE STANDARD CYTOGENETIC STUDY OF BONE MARROW CELLS IN THE DIAGNOSIS OF ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN 
    Zauatbayeva, G.; Tolegen, N.; Bayanova, M. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Acute lymphoblastic leukemia is a disease of the hematopoietic system caused by a violation of certain functions of the bone marrow. The disease is characterized by excessive proliferation of white blood ...