DSpace Repository

Recently added

MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE: Recent submissions

  • СЕРОТИПИРОВАНИЕ И ПОКАЗАТЕЛИ ЗАБОЛЕВАЕМОСТИ МЕНИНГОКОККОВОЙ ИНФЕКЦИИ У ДЕТЕЙ В Г.НУР-СУЛТАН 
    Кожахметов, C.C.; Сейдуллаева, А.Ж.; Баешева, Д.А.; Турдалина, Б.Р.; Омарова, А.К.; Волкова, Г.С.; Нуртазина, Г.Г.; Руденко, В.В. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Актуальность проблемы заключается в том, что среди инвазивных инфекций менингококковая инфекция требует особого подхода к организации диагностики и оказанию скорой и неотложной медицинской помощи ввиду того, что ее ...
  • ПОЛИМОРФНЫЕ ГЕНЕТИЧЕСКИЕ МАРКЕРЫ И ИХ АССОЦИАЦИИ С КЛИНИКО-МЕТАБОЛИЧЕСКИМИ ПОКАЗАТЕЛЯМИ САХАРНОГО ДИАБЕТА 2-ГО ТИПА В КАЗАХСКОЙ ПОПУЛЯЦИИ 
    Нагимтаева, А.А.; Бенберин, В.В.; Вощенкова, Т.А.; Абильдинова, Г.Ж.; Боровикова, А.В.; Жабакова, Ж.М.; Сибагатова, А.С.; Ахметова, К.М. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Введение. Неуклонный рост больных с СД2в РК за последние десятилетия указывает на необходимость разработки программы по профилактике СД. Цель настоящего исследования - анализ ассоциации полиморфных маркеров с биохимическими и ...
  • ИЗУЧЕНИЕ ПОЛИМОРФИЗМОВ ГЕНОВ АССОЦИИРОВАННЫХ С РАЗВИТИЕМ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ В КАЗАХСКОЙ ПОПУЛЯЦИИ 
    Сейдалин, Н.К.; Бенберин, В.В.; Шаназаров, Н.А.; Жаппаров, Е.И.; Арипжанова, Г.О.; Бабенко, Д.Б. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Введение. Рак молочной железы (РМЖ) является самой распространенной злокачественной опухолью у женщин. Заболеваемость РМЖ неуклонно возрастает. Распространенность, высокий индекс инвалидизации, экономические затраты на ...
  • TARGETED NEXT GENERATION SEQUENCING REVEALS NEW INSIGHTS INTO THE GENETIC BASIS OF INHERITED ARRHYTHMIA IN KAZAKHSTANI PATIENTS 
    Akilzhanova, A.; Guelly, C.; Abilova, Zh.; Rakhimova, S.; Akhmetova, A.; Kairov, U.; Trajanoski, S.; Akilzhanova, G.; Kozhamkulov, U.; Abdrakhmanov, A.; Bekbosynova, M. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction:Ventricular arrhythmias are caused by mutations of ion channels and their interacting proteins. Most arrhythmia syndromes are inherited in an autosomal dominant manner, such that first-degree family members ...
  • GENETIC VARIANTS, METABOLOME, AND GUT MICROBIOME BIOMARKERS FOR OBESITY AND AGING IN RANDOMLY SELECTED KAZAKH INDIVIDUALS 
    Akilzhanova, Ainur; Rakhimova, Saule; Kozhamkulov, Ulan; Kairov, Ulykbek; Kushugulova, Almagul R.; Terwilliger, Joseph; Lee, Joseph (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Objective: Metabolic syndrome (MS) is a cluster of inter-related and heritable metabolic traits, which collectively impart unsurpassed risk for atherosclerotic cardiovascular disease and type 2diabetes. Considerable work ...
  • GENOTYPING OF MYCOBACTERIUM TUBERCULOSIS ISOLATES AMONG RECURRENT CASES OF TUBERCULOSIS IN KAZAKHSTAN 
    Akhmetova, A.; Akilzhanova, A.; Toksanbaeva, B.; Bismilda, V.; Chingissova, L.; Kozhamkulov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Tuberculosis still remains one of the major health problems in Kazakhstan. According to the World Health Organization data (2018), Kazakhstan is on the list of 30 countries with high rates of multidrug ...
  • DRUG RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS CLINICAL ISOLATES FROM NEW TB CASES IN KAZAKHSTAN 
    Kozhamkulov, U.; Akhmetova, A.; Rakhimova, S.; Daniyarov, A.; Molkenov, A.; Bismilda, V.; Chingissova, L.; Kairov, U.; Akilzhanova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Nowadays and worldwide, TB is one of the top 10 causes of death and the leading cause from a single infectious agent. The global incidence of drug-susceptible TB, multidrug-resistant (MDR) and extensively ...
  • SNPS ASSOCIATED WITH MYOCARDIUM REMODELING IN HYPERTENSION IN THE KAZAKH POPULATION 
    Sibagatova, A.; Benberin, V.; Karabayeva, R.; Vochshenkova, T.; Nagimtayeva, A.; Akhmetova, K.; Babenko, D. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Cardiovascular Disease (CVD) is the leading cause of mortality in Kazakhstan. Among all CVDs, hypertension is the most common and leads to remodeling of myocardium, which significantly increases cardiovascular ...
  • WHOLE TRANSCRIPTOME SEQUENCING ANALYSIS OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA FROM KAZAKHSTAN 
    Sharip, A.; Rakhimova, S.; Molkenov, A.; Kozhamkulov, U.; Zhukov, Y.; Omarov, M.; Akilzhanova, A.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Esophageal cancer is the eighth most common cancer worldwide and sixth in Kazakhstan. Esophageal squamous cell carcinoma (ESCC) is the predominant histological subtype of esophageal cancer and diagnosed at ...
  • POTASSIUM CHANNEL GENES KCNQ1, KCNE1/2, KCNH2 (HERG) MUTATIONS IN PATIENTS WITH ATRIAL FIBRILLATION IN KAZAKHSTAN 
    Abilova, Zhannur; Rakhimova, Saule; Akhmetova, Ainur; Zhalbinova, Madina; Nuralinov, Omirbek; Rashbayeva, Gulzhaina; Akilzhanova, Gulbanu; Abdrakhmanov, Ayan; Bekbosynova, Mahabbat; Akilzhanova, Ainur (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Background: Atrial fibrillation (AF) is a common arrhythmia of substantial public health importance, a major risk factor for stroke, heart failure, and other cardiovascular morbidities. Recent evidence demonstrates a ...
  • ЦИТОПРОТЕКТОРНЫЙ ПОТЕНЦИАЛ ЭКСТРАКТОВ КЛЮКВЫ, БРУСНИКИ, ЧЕРНИКИ 
    Жуликеева, А.; Сегизбаева, Г.; Шульгау, З.; Харитонова, М.; Гуляев, А.; Кривых, E.; Сергазы, Ш. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Терапевтический потенциал северных ягод связывают с высоким содержанием полифенольных субстанций. Экстракты клюквы, брусники, черники вследствие высокого содержания полифенолов, способны обладать антиоксидантными и ...
  • ИЗУЧЕНИЕ ФУНКЦИОНАЛЬНЫХ СВОЙСТВ МИКРООРГАНИЗМОВ, ВЫДЕЛЕННЫХ ИЗ ВЕРБЛЮЖЬЕГО МОЛОКА 
    Кудайбергенова, А. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Изучение пробиотических свойств микроорганизмов, на сегодняшний день получило широкое распространение, но не утратило актуальности. Препараты на основе молочнокислых бактерий используются для лечения и профилактики ...
  • ГЕНОМНАЯ ХАРАКТЕРИСТИКА КИШЕЧНЫХ ШТАММОВ KL. PNEUMONIAE, ВЫДЕЛЕННЫХ У НОВОРОЖДЕННЫХ ДЕТЕЙ В РОДИЛЬНОМ ДОМЕ 
    Николаева, И.; Шайхиев, Г.; Григорьева, Т.; Васильев, И. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Кl. pneumoniae являются одними из первых колонизаторов кишечника новорожденных и способны вызывать местные и системные заболевания в форме инфекции и мочевых путей, менингита, пневмонии, неонатального сепсиса. В связи ...
  • ОПРЕДЕЛЕНИЕ ПРОБИОТИЧЕСКИХ СВОЙСТВ ДРОЖЖЕЙ SACCHAROMYCESCEREVISIAE 
    Сапарбекова, А.; Латиф, A.; Ахмедова, З. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Введение: В традиционной ферментированной пище образуются ряд веществ потенциально полезные для здоровья человека. Использование пробиотических культур, позволяют получить продукцию, содержащую эти культуры, за счет ...
  • CLINICAL EVALUATION OF THE EFFECTIVENESS OF MARE’S MILK IN PSORIASIS 
    Algazina, T.; Yermekbayeva, B.; Batpenova, G.; Kozhakhmetov, S.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    According to the world health organization, the prevalence of psoriasis in the world is about 2%. However, according to a number of studies, this figure is significantly higher in developed countries and can range from ...
  • STRUCTURAL CHANGES IN THE MICROBIOME IN RATS WITH DSS-INDUCED COLITIS 
    Kozhakhmetov, S.; Babenko, D.; Tuyakova, A.; Nurgaziyev, M.; Nurgozhina, A.; Muhanbetganov, N.; Chulenbayeva, L.; Sergazy, S.; Gulyayev, A.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Microflora plays a critical role in the initiation and development of inflammatory bowel disease (IBD). There are many facts accumulated about the effect of intestinal dysbiosis on the pathogenesis of Crohn’s disease and ...
  • EFFECT OF MARE’S MILK PREBIOTIC SUPPLEMENTATION ON THE GUT MICROBIOME AND THE IMMUNE SYSTEM DURING AND AFTER ANTIBIOTIC THERAPY 
    Nurgaziyev, M.; Aitenov, Y.; Khassenbekova, Zh.; Akpanova, S.; Rysbekov, K.; Kozhakhmetov, S.; Nurgozhina, A.; Sergazy, Sh.; Chulenbayeva, L.; Ospanova, Zh.; Tuyakova, A.; Mukhambetganov, N.; Sattybayeva, R.; Urazova, S.; Galymgozhina, N.; Gulyaev, A.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Antibiotic treatment can severely affect the gut microbiome with short-term and long-term consequences. Probiotic and prebiotic supplements are widely prescribed to modulate the composition and function of the human gut ...
  • SPECIFICATIONS OF NUTRITION WITH HEALTHY AND PATHOLOGICAL CONDITIONS OF PSORIASIS 
    Nurgozhina, A.; Yermekbayeva, B.; Gulyayev, A.; Kozhakhmetov, S.; Sergazy, S.; Nurgaziyev, M.; Aitenov, Y.; Chulenbayeva, L.; Tuyakova, A.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. 183 participants in the experiment were selected for the study, half of which are with psoriasis disease. All participants in the ...
  • ISOLATION FROM THE KAZAKH TRADITIONAL FOOD PRODUCTS OF A NEW STRAIN OF LACTIC ACID BACTERIA PRODUCING THE HUMAN PLASMINOGEN RECEPTOR 
    Shaikhin, S.; Abitayeva, G.; Abilhadirov, A.; Dossova, A.; Pirmanova, A.; Tynybaeva, I. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Lactobacillus bacteria are one of the most important groups of the human intestinal microbiota that promote health. Adhesion to host tissues represents a crucial early step in the colonization process of either pathogens ...
  • ENGINEERING CHEMOKINE-BASED CCR5 BLOCKERS TO TACKLE INFECTIOUS AND INFLAMMATORY DISEASES 
    Vangelista, Luca (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    The C-C chemokine receptor type 5, CCR5, is expressed on various cell types and is involved in a large number of pathophysiological conditions. In recent years, CCR5 gained a huge attention, as it was found to play a ...