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Browsing Articles by Author "3708e577-5d50-4b24-a802-873140ec7095"

Browsing Articles by Author "3708e577-5d50-4b24-a802-873140ec7095"

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  • Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G 
    Eipper, Steffen; Steiner, Robin; Lesner, Adam; Sienczyk, Marcin; Palesch, David; Halatsch, Marc- Eric; Zaczynska, Ewa; Heim, Christopher; Hartmann, Marcus D.; Zimecki, Michal; Rainer Wirtz, Christian; Burster, Timo (PLOS ONE, 2016-03-17)
    Protease-mediated degradation of proteins is critical in a plethora of physiological processes. Neutrophils secrete serine proteases including cathepsin G (CatG), neutrophile elastase (NE), and proteinase 3 (PR3) together ...
  • Regulation of Cathepsin G Reduces the Activation of Proinsulin-Reactive T Cells from Type 1 Diabetes Patients 
    Zou, Fang; Schafer, Nadja; Palesch, David; Brucken, Ruth; Beck, Alexander; Sienczyk, Marcin; Kalbacher, Hubert; Sun, ZiLin; Boehm, Bernhard O.; Burster, Timo (PLoS ONE, 2011-08-05)
    Autoantigenic peptides resulting from self-proteins such as proinsulin are important players in the development of type 1 diabetes mellitus (T1D). Self-proteins can be processed by cathepsins (Cats) within endocytic ...