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  • Iskakova, Aisha N.; Romanova, Aliya A.; Aitkulova, Akbota M.; Sikhayeva, Nurgul S.; Zholdybayeva, Elena V.; Ramanculov, Erlan M. (BMC Genetics, 2016-01-19)
    Background: Studies of genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are crucial to the development of therapeutics in clinical medicine. Such data provide information that may ...
  • Zholdybayeva, Elena V.; Talzhanov, Yerkebulan A.; Aitkulova, Akbota M.; Tarlykov, Pavel V.; Kulmambetova, Gulmira N.; Iskakova, Aisha N.; Dzholdasbekova, Aliya U.; Visternichan, Olga A.; Taizhanova, Dana Zh.; Ramanculov, Yerlan M. (Human Genomics, 2016)
    Background: After coronary stenting, the risk of developing restenosis is from 20 to 35 %. The aim of the present study is to investigate the association of genetic variation in candidate genes in patients diagnosed with ...
  • Sikhayeva, Nurgul; Iskakova, Aisha; Saigi-Morgui, Nuria; Zholdybaeva, Elena; Eap, Chin-Bin; Ramanculov, Erlan (BMC Medical Genetics, 2017-07-24)
    Background: We evaluated the associations between single nucleotide polymorphisms and different clinical parameters related to type 2 diabetes mellitus (T2DM), obesity risk, and metabolic syndrome (MS) in a Kazakh cohort. ...
  • Shevtsova, Elena; Shevtsov, Alexandr; Mukanov, Kasim; Filipenko, Maxim; Kamalova, Dinara; Sytnik, Igor; Syzdykov, Marat; Kuznetsov, Andrey; Akhmetova, Assel; Zharova, Mira; Karibaev, Talgat; Tarlykov, Pavel; Ramanculov, Erlan (Plos One, 2016-12-01)
    Brucellosis is a major zoonotic infection in Kazakhstan. However, there is limited data on its incidence in humans and animals, and the genetic diversity of prevalent strains is virtually unstudied. Additionally, there is ...
  • Pappalardo, Francesco; Brusic, Vladimir; Pennisi, Marzio; Zhang, Guanglan (Journal of Immunology Research, 2015)
  • Pappalardo, Francesco; Brusic, Vladimir; Castiglione, Filippo; Schönbach, Christian (BioMed Research International, 2014-12-31)
  • Kim, Yevgeniy; Kim, Aleksei; Sharip, Ainur; Sharip, Aigul; Jiang, Juhong; Yang, Qing; Xie, Yingqiu (International Journal of Biological Sciences, 2017-02-17)
    One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating ...
  • Zhubanchaliyev, Altynbek; Temirbekuly, Aibar; Kongrtay, Kuralay; Wanshura, Leah C.; Kunz, Jeannette (Frontiers in Pharmacology, 2016-12-01)
    Liver fibrosis is the result of a deregulated wound healing process characterized by the excessive deposition of extracellular matrix. Hepatic stellate cells (HSCs), which are activated in response to liver injury, are the ...
  • Aituov, Bauyrzhan; Duisembekova, Assem; Bulenova, Assel; Alibek, Kenneth (Infectious Agents and Cancer, 2012)
    The regulation of cancerous tumor development is converged upon by multiple pathways and factors. Besides environmental factors, gastrointestinal (GI) tract cancer can be caused by chronic inflammation, which is generally ...
  • Ranganathan, Shoba; Tan, Tin Wee; Schönbach, Christian (BMC Bioinformatics, 2014-12-08)
    Since 2006, the International Conference on Bioinformatics (InCoB) has been publishing selected papers in BMC Bioinformatics. Papers within the scope of the journal from the 13th InCoB July 31-2 August, 2014 in Sydney, ...
  • Schönbach, Christian; Horton, Paul; Yiu, Siu Ming; Tan, Tin Wee; Ranganathan, Shoba (BMC Bioinformatics, 2015-12-18)
    GIW/InCoB2015 the joint 26th International Conference on Genome Informatics (GIW) and 14th International Conference on Bioinformatics (InCoB) held in Tokyo, September 9-11, 2015 was attended by over 200 delegates. Fifty-one ...