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  • Sun, Xiaoming; Shi, Yi; Akahoshi, Tomohiro; Fujiwara, Mamoru; Gatanaga, Hiroyuki; Schönbach, Christian; Kuse, Nozomi; Appay, Victor; Gao, George F.; Oka, Shinichi; Takiguchi, Masafumi (Cell Reports, 2016-06-07)
    Summary The mechanistic basis for the progressive accumulation of Y135F Nef mutant viruses in the HIV-1-infected population remains poorly understood. Y135F viruses carry the 2F mutation within RW8 and RF10, which are two ...
  • Barteneva, Natasha S.; Baiken, Yeldar; Fasler-Kan, Elizaveta; Alibek, Kenneth; Wang, Sheng; Maltsev, Natalia; Ponomarev, Eugene D.; Sautbayeva, Zarina; Kauanova, Sholpan; Moore, Anna; Beglinger, Christoph; Vorobjev, Ivan A. (Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2017-12-01)
    Abstract Extracellular vesicle (EV) production is a universal feature of metazoan cells as well as prokaryotes (bMVs - bacterial microvesicles). They are small vesicles with phospholipid membrane carrying proteins, DNA and ...
  • Masutani, Mitsuko; Baiseitov, Diaz; Itoh, Tasuku; Hirai, Takahisa; Berikkhanova, Kulzhan; Murakami, Yasufumi; Zhumadilov, Zhaxybay; Imahori, Yoshio; Hoshi, Masaharu; Itami, Jun (Applied Radiation and Isotopes, 2014-06-01)
    Abstract To understand the mechanism of tumor cell death induced by boron neutron capture therapy (BNCT) and to optimize BNCT condition, we used rat tumor graft models and histological and biochemical analyses were carried ...
  • Jin, Yong-Ri; Stohn, J. Patrizia; Wang, Qiaozeng; Nagano, Kenichi; Baron, Roland; Bouxsein, Mary L.; Rosen, Clifford J.; Adarichev, Vyacheslav A.; Lindner, Volkhard (Bone, 2017-04-01)
    Abstract Collagen triple helix repeat-containing1 (Cthrc1) has previously been implicated in osteogenic differentiation and positive regulation of bone mass, however, the underlying mechanisms remain unclear. Here we ...
  • Shevtsov, Alexandr; Ramanculov, Erlan; Shevtsova, Elena; Kairzhanova, Alma; Tarlykov, Pavel; Filipenko, Maxim; Dymova, Maya; Abisheva, Gulzada; Jailbekova, Aygul; Kamalova, Dinara; Chsherbakov, Andrei; Tulegenov, Samat; Akhmetova, Assel; Sytnik, Igor; Karibaev, Talgat; Mukanov, Kasim (Infection, Genetics and Evolution, 2015-08-01)
    Abstract Brucellosis is an endemic disease in Central Asia characterized by high infection rates in humans and animals. Currently, little is known about the genetic diversity of Brucella spp. circulating in the region, ...
  • Haridas, Viraga; Ranjbar, Shahin; Vorobjev, Ivan A.; Goldfeld, Anne E.; Barteneva, Natasha S. (Methods, 2017-01-01)
    Abstract Imaging flow cytometry has been applied to address questions in infection biology, in particular, infections induced by intracellular pathogens. This methodology, which utilizes specialized analytic software makes ...
  • Vorobjev, Ivan A.; Barteneva, Natasha S. (Methods, 2017-01-01)
    Abstract Apoptosis is a multistep process of programmed cell death where different morphological and molecular events occur simultaneously and/or consequently. Recent progress in programmed cell death analysis uncovered ...
  • Dashkova, Veronika; Malashenkov, Dmitry; Poulton, Nicole; Vorobjev, Ivan; Barteneva, Natasha S. (MethodsMethods, 2017-01-01)
    Abstract This review highlights the concepts and instrumentation of imaging flow cytometry technology and in particular its use for phytoplankton analysis. Imaging flow cytometry, a hybrid technology combining speed and ...
  • Stauffer, Fritz; Griess, Marion; Pleininger, Gabriele; Zhumadilova, Anara; Assadian, Ojan (American Journal of Infection Control, 2013-11-01)
    BackgroundHand hygiene is effective to prevent the transmission of microorganisms in health care settings, but compliance remains low, even when easy access to hand cleaning agents is provided. ObjectiveFormulation of ...
  • Goerdt, Anna-Maria; Assadian, Ojan; Razavi, Behzad; Igelbrink-Holter, Dorothee; Simon, Arne; Hübner, Nils-Olaf; Partecke, Lars Ivo; Zhumadilova, Anara; Heidecke, Claus-Dieter; Kramer, Axel (Wound Medicine, 2013-07-01)
    Abstract PurposeThe antimicrobial efficacy of medical honeys used for professional wound care was published previously. So far, all in vitro antimicrobial tests performed have been conducted using non-standardized methods ...
  • Dickie, Diane A.; Chacon, Brittany E.; Issabekov, Alibek; Lam, Kevin; Kemp, Richard A. (Inorganica Chimica Acta, 2016-11-01)
    Abstract In its neutral state, bis(diisopropylphosphino)amine HL reacts in equimolar amounts with the nickel halides NiCl2·6H2O, NiBr2, and NiI2 in ethanol solutions to give the air- and moisture-stable P,P-chelated complexes ...
  • Ibragimova, Nazgul; Zhanzak, Zhuldyz; Meyerbekova, Aizhan; Xie, Yingqiu (European Urology, 2018-01-01)
    Egger et al performed a 10-yr cohort study among 52–79-yr-old men diagnosed with low-risk localized prostate cancer. The objective of this research was to test permanent psychological and quality-of-life effects after ...
  • Iskakova, Aisha N.; Romanova, Aliya A.; Aitkulova, Akbota M.; Sikhayeva, Nurgul S.; Zholdybayeva, Elena V.; Ramanculov, Erlan M. (BMC Genetics, 2016-01-19)
    Background: Studies of genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are crucial to the development of therapeutics in clinical medicine. Such data provide information that may ...
  • Zholdybayeva, Elena V.; Talzhanov, Yerkebulan A.; Aitkulova, Akbota M.; Tarlykov, Pavel V.; Kulmambetova, Gulmira N.; Iskakova, Aisha N.; Dzholdasbekova, Aliya U.; Visternichan, Olga A.; Taizhanova, Dana Zh.; Ramanculov, Yerlan M. (Human Genomics, 2016)
    Background: After coronary stenting, the risk of developing restenosis is from 20 to 35 %. The aim of the present study is to investigate the association of genetic variation in candidate genes in patients diagnosed with ...
  • Sikhayeva, Nurgul; Iskakova, Aisha; Saigi-Morgui, Nuria; Zholdybaeva, Elena; Eap, Chin-Bin; Ramanculov, Erlan (BMC Medical Genetics, 2017-07-24)
    Background: We evaluated the associations between single nucleotide polymorphisms and different clinical parameters related to type 2 diabetes mellitus (T2DM), obesity risk, and metabolic syndrome (MS) in a Kazakh cohort. ...
  • Shevtsova, Elena; Shevtsov, Alexandr; Mukanov, Kasim; Filipenko, Maxim; Kamalova, Dinara; Sytnik, Igor; Syzdykov, Marat; Kuznetsov, Andrey; Akhmetova, Assel; Zharova, Mira; Karibaev, Talgat; Tarlykov, Pavel; Ramanculov, Erlan (Plos One, 2016-12-01)
    Brucellosis is a major zoonotic infection in Kazakhstan. However, there is limited data on its incidence in humans and animals, and the genetic diversity of prevalent strains is virtually unstudied. Additionally, there is ...
  • Pappalardo, Francesco; Brusic, Vladimir; Pennisi, Marzio; Zhang, Guanglan (Journal of Immunology Research, 2015)
  • Pappalardo, Francesco; Brusic, Vladimir; Castiglione, Filippo; Schönbach, Christian (BioMed Research International, 2014-12-31)
  • Kim, Yevgeniy; Kim, Aleksei; Sharip, Ainur; Sharip, Aigul; Jiang, Juhong; Yang, Qing; Xie, Yingqiu (International Journal of Biological Sciences, 2017-02-17)
    One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating ...
  • Zhubanchaliyev, Altynbek; Temirbekuly, Aibar; Kongrtay, Kuralay; Wanshura, Leah C.; Kunz, Jeannette (Frontiers in Pharmacology, 2016-12-01)
    Liver fibrosis is the result of a deregulated wound healing process characterized by the excessive deposition of extracellular matrix. Hepatic stellate cells (HSCs), which are activated in response to liver injury, are the ...

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