Type 1 Diabetes: Current Perspectives

dc.contributor.author	Kozhakhmetova, A
dc.contributor.author	Gillespie, KM
dc.date.accessioned	2019-09-09T09:45:46Z
dc.date.available	2019-09-09T09:45:46Z
dc.date.issued	2016
dc.identifier.citation	Kozhakhmetova A(1), Gillespie KM(2). Type 1 Diabetes: Current Perspectives. Methods Mol Biol. 2016;1433:1-9. doi: 10.1007/7651_2015_289.	en_US
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/4228
dc.description.abstract	Type 1 diabetes, resulting from the autoimmune destruction of insulin producing islet beta cells is caused by genetic and environmental determinants. Recent studies agree that counterintuitively, the major genetic susceptibility factors are decreasing in frequency as the incidence of the condition increases. This suggests a growing role for environmental determinants but these have been difficult to identify and our understanding of gene/environment effects are limited. Individuals "at-risk" can be identified accurately through the presence of multiple islet autoantibodies and current efforts in type 1 diabetes research focus on improved biomarkers and strategies to prevent or reverse the condition through immunotherapy.	en_US
dc.language.iso	en	en_US
dc.publisher	Methods in Molecular Biology	en_US
dc.subject	Autoimmunity; Genes; Insulin; Islet autoantibodies; Type 1 diabetes	en_US
dc.title	Type 1 Diabetes: Current Perspectives	en_US
dc.type	Book chapter	en_US
workflow.import.source	science