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Browsing Biology by Title
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Vorobyev, Ivan; Zorov, Dmitry; Popkov, Vasily; Babenko, Valentina; Zorova, Ljubava; Pevzner, Irina; Silachev, Denis; Zorov, Savva; Andrianova, Nadezda; Plotnikov, Egor
(Nazarbayev University School of Sciences and Humanities, 2019-02-20)
Thirty-five years ago, we described fragmentation of the mitochondrial population in a living cell into small vesicles (mitochondrial fission). Subsequently, this phenomenon has become an object of general interest due to ...
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Xu, Juan; Yang, WenTao; Pan, YiFeng; Xu, HaiShun; He, Liang; Zheng, BingSong; Xie, YingQiu; Wu, XueQian
(Food and Chemical Toxicology, 2022)
High infection caused by mutations of SARS-CoV-2 calls for new prevention strategy. Ganoderma lucidum known
as a superior immunoenhancer exhibits various antiviral effects, whether it can resist SARS-CoV-2 remains ...
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Len, Polina; Iskakova, Gaukhar; Sautbayeva, Zarina; Kussanova, Aigul; Tauekelova, Ainur; Sugralimova, Madina; Abdieva, Meruert; Ponomarev, Eugene; Tikhonov, Alexander; Bekbossynova, Makhabbat; Barteneva, Natasha
(Frontiers Media, 2022-03-11)
Introduction: Coagulation parameters are important determinants for COVID-19 infection. We conducted meta-analysis to assess the association between early hemostatic parameters and infection severity.
Methods: Electronic ...
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Seisenova, Ainur; Daniyarov, Asset; Molkenov, Askhat; Sharip, Aigul; Zinovyev, Andrei; Kairov, Ulykbek
(Frontiers in Genetics, 2021)
Independent Component Analysis is a matrix factorization method for data dimension
reduction. ICA has been widely applied for the analysis of transcriptomic data for blind
separation of biological, environmental, and ...
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Tarlykov, Pavel; Atavliyeva, Sabina; Auganova, Dana; Akhmetollayev, Ilyas; Loshakova, Tatyana; Varfolomeev, Victor; Ramankulov, Yerlan
(Heliyon, 2021-09-16)
Kazakhstan covers a vast territory, and it has always been a land of nomadic pastoralism, where domesticated horses and sheep were moved by nomadic people across the steppe. Previous reports suggest that sheep breeds from ...
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Soltabayeva, Aigerim; Ongaltay, Assel; Omondi, John Okoth; Srivastava, Sudhakar
(Plants, 2021-01-27)
Plant growth and development is adversely affected by different kind of stresses. One of the major abiotic stresses, salinity, causes complex changes in plants by influencing the interactions of genes. The modulated genetic ...
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Barteneva, Natasha S.
(Nazarbayev University School of Sciences and Humanities, 2018-11-28)
The importance of myeloid cells in HIV transmission in the female genital tract is uncertain. Because it is difficult to study the early events in HIV transmission in humans, most of our knowledge is based on animal models ...
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Saidova, Aleena A.; Potashnikova, Daria M.; Tvorogova, Anna V.; Paklina, Oxana V.; Veliev, Evgeniy I.; Knyshinsky, Grigoriy V.; Setdikova, Galiya R.; Rotin, Daniil L.; Maly, Ivan V.; Hofmann, Wilma A.; Vorobjev, Ivan A.
(Public Library of Science, 2021-05-21)
Early diagnosis of prostate cancer is a challenging issue due to the lack of specific markers. Therefore, a sensitive diagnostic marker that is expressed or upregulated exclusively in prostate cancer cells would facilitate ...
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Nazarbek, Guldan; Kutzhanova, Aidana; Nurtay, Lazzat; Mu, Chenglin; Kazybay, Bexultan; Li, Xugang; Ma, Cuiping; Amin, Amr; Xie, Yingqiu
(Nanoscale Advances, 2021)
Nanozymes and natural product-derived herbzymes have been identified in different types of enzymes simulating the natural protein-based enzyme function. How to explore and predict enzyme types of novel nanozymes when ...
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Kazybay, Bexultan; Sun, Qinglei; Dukenbayev, Kanat; Nurkesh, Ayan Amantaiuly; Xu, Na; Kutzhanova, Aidana; Razbekova, Madina; Kabylda, Anar; Yang, Qing; Wang, Qian; Ma, Cuiping; Xie, Yingqiu
(ACS Applied Bio Materials, 2022)
A combination therapy of Rhizoma Polygonati (RP) with goji (Lycium chinense) has earned a long history in the prescriptions to promote male health. However, the mechanisms at both molecular and nanoscale quantum levels are ...
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Mustafa, Zhadyra; Zhanapiya, Anuar; Kalbacher, Hubert; Burster, Timo
(American Chemical Society Omega, 2021-03-05)
Serine proteases neutrophil elastase (NE), protease 3 (PR3), cathepsin G (CatG), and neutrophil serine protease 4 (NSP4) are released by activated neutrophils swarming around the place of pathogen invasion to provoke an ...
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Meirkhanova, Ayagoz
(Nazarbayev University School of Sciences and Humanities, 2022)
Increasing evidence reports adverse effects of climate change on freshwater ecosystems
and harmful algal blooms in particular, but response mechanisms of such heterogeneous
communities are poorly understood. Environmental ...
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Zvorykina, Yekaterina; Tvorogova, Anna; Gladkikh, Aleena; Vorobyev, Ivan
(AIMS Press, 2018)
Microtubules in interphase fibroblast-like cells are thought to be organized in a radial array growing from a centrosome-based microtubule-organizing center (MTOC) to the cell edges. However, many morphogenetic processes ...
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Potashnikova, Daria; Saidova, Aleena; Tvorogova, Anna; Sheval, Eugene; Vorobjev, Ivan
(FRONTIERS MEDIA, 2019-04-24)
Microtubule (MT) inhibitors show anti-cancer activity in a wide range of tumors in vitro and demonstrate high clinical efficacy. To date they are routinely included into many chemotherapeutic regimens. While the mechanisms ...
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Xie, Yingqiu; Fan, Haiyan; Wenfu, Lu; Yang, Qing; Nurkesh, Ayan; Yeleussizov, Tleubek; Maipas, Aisulu; Lu, Jiang; Manarbek, L.; Chen, Zh.; Benassi, E.
(Nazarbayev University School of Sciences and Humanities, 2019-04-18)
Nuclear receptor tyrosine kinases (nRTKs) are aberrantly upregulated in many types of cancers, but the regulation of nRTK remains unclear. We previously showed androgen deprivation therapy (ADT) induces nMET in ...
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Mustafa, Zhadyra; Kalbacher, Hubert; Burster, Timo
(PLOS ONE, 2022)
The serine proteases neutrophil elastase (NE), proteinase 3 (PR3), cathepsin G (CatG),
and neutrophil serine protease 4 (NSP4) are secreted by activated neutrophils as a part of
the innate immune response against invading ...
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Kazybay, Bexultan; Ahmad, Ashfaq; Mu, Chenglin; Mengdesh, Diana; Xie, Yingqiu
(Travel Medicine and Infectious Disease, 2022)
Variants of SARS-CoV-2 lineages including the most recently circulated Omicron, and previous pandemic
B.1.351, B.1.1.7, which have been public concerns, contain a N501Y mutation located in the spike receptor
binding ...
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Abidi, Syed Hani; Aibekova, Lazzat; Davlidova, Salima; Amangeldiyeva, Aidana; Foley, Brian; Ali, Syed
(PLOS ONE, 2021)
HIV outbreaks in the Former Soviet Union (FSU) countries were characterized by repeated transmission of the HIV variant AFSU, which is now classified as a distinct subtype A sub-subtype called A6. The current study used ...
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Abidi, Syed Hani; Aibekova, Lazzat; Davlidova, Salima; Amangeldiyeva, Aidana; Foley, Brian; Ali, Syed
(PLoS One, 2021-12)
Background: HIV outbreaks in the Former Soviet Union (FSU) countries were characterized by repeated transmission of the HIV variant AFSU, which is now classified as a distinct subtype A sub-subtype called A6. The current ...
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Burakov, Anton; Vorobjev, Ivan; Cowan, Ann; Carson, John; Wu, Yi; Rodionov, Vladimir
(Molecular Biology of the Cell, 2021-03-21)
Microtubules (MTs) often form a polarized array with minus ends anchored at the centrosome and plus ends extended toward the cell margins. Plus ends display behavior known as dynamic instability—transitions between rapid ...