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Browsing Biology by Author "aade61d0-cebf-4ed8-86f9-f6033d8e2823"
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Tvorogova, Anna; Saidova, Aleena; Smirnova, Tatiana; Vorobjev, Ivan
(Biology Open, 2018-12-13)
When cells with a mesenchymal type of motility come into contact with an adhesive substrate they adhere and start spreading by the formation of lamellipodia. Using a label-free approach and virtual synchronization approach ...
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Kauanova, Sholpan; Urazbayev, Arshat; Vorobjev, Ivan
(Front. Cell Dev. Biol., 2021-03-11)
Wound healing assay performed with automated microscopy is widely used in drug
testing, cancer cell analysis, and similar approaches. It is easy to perform, and the
results are reproducible. However, it is usually used ...
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Potashnikova, Daria; Saidova, Aleena; Tvorogova, Anna; Sheval, Eugene; Vorobjev, Ivan
(FRONTIERS MEDIA, 2019-04-24)
Microtubule (MT) inhibitors show anti-cancer activity in a wide range of tumors in vitro and demonstrate high clinical efficacy. To date they are routinely included into many chemotherapeutic regimens. While the mechanisms ...
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Burakov, Anton; Vorobjev, Ivan; Cowan, Ann; Carson, John; Wu, Yi; Rodionov, Vladimir
(Molecular Biology of the Cell, 2021-03-21)
Microtubules (MTs) often form a polarized array with minus ends anchored at the centrosome and plus ends extended toward the cell margins. Plus ends display behavior known as dynamic instability—transitions between rapid ...