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Browsing Materials of conferences and seminars by Issue Date

Browsing Materials of conferences and seminars by Issue Date

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  • Migration characteristics of cell grown in embryonic microenvironment and under antiviral agents 
    Karapina, O.; Shaimerdenova, M.; Mektepbayeva, D.; Akilbekova, D. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Cancer metastasis is a crucial process of spread of cancer cells from the origin of tumor lesion to the tissues and other organs beyond, where new tumor lesions are formed which might be a single kick of event that may ...
  • Molecular-genetical tumor parameters at patients with lung cancer taking into account smoking factor 
    Smagulova, G.; Zhylkaydarova, A.; Tuleuhanov, S.; Esentayeva, S.; Baimukhametov, E.; Goncharova, T.; Sokolenko, E.; Kerimov, A. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    In Kazakhstan lung cancer takes the first place in the cancer morbidity and cancer mortality structure. Tobacco smoking (TS) remains the most established cause of lung carcinogenesis and other disease processes. ...
  • Biomechanical properties of collagens studied by brillouin light scattering spectroscopy and atomic force microscopy 
    Akilbekova, D.; Alimzhanov, D.; Utegulov, Zh. (2016-05)
    Collagen is the most abundant protein in the human body and the main component of highly organized tissue structures. Its fibrillar structure is responsible for biomechanical anisotropies in the tissues and their exceptional ...
  • Development of a new method of surgical treatment of patellofemoral pain syndrome 
    Akilzhanov, K. (2016-05)
    Patellofemoral pain syndrome (PFBS) - one of the most frequent symptom in orthopedic practice. According to available statistics, from 18% to 33% of all calls to the Orthopaedic Trauma and sports doctors about the pathology ...
  • Restoration of mesenchymal stem cell function using pharmacological agents 
    Masoud, A.; Umbayev, B.; Shramko, A.; Idrissova, D. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    The extensive characteristics of mesenchymal stem cells (MSCs), especially their capacity to replicate and differentiate into any type of fully developed cell make these cells suitable for use in cell therapy. These cells ...
  • D-serine improves learning and memory in epileptic animals 
    Tokay, T.; Mueller, L.; Xie, Y.; Kirschstein, T.; Beck, H.; Koehling, R. (2016-05)
    The N-methyl-D-aspartate receptor (NMDAR) is critical for the induction of synaptic plasticity and is essential for many forms of learning and memory. Activation of NMDAR by glutamate requires the presence of D-Serine, ...
  • Rapid evaluation of DNA damage with comet assay in combination of high throughput microscopy 
    Baiskhanova, D.; Bobrova, X.; Kauanova, S.; Begimbetova, D. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Comet assay is well known method for DNA damage evaluation. However, it also possesses some limitations related to the problem with manual entry of each comet for analysis that decreases the performance and measurement ...
  • HLA-B27 subtypes distribution among the healthy population in Kazakhstan 
    Shuinshkalieva, Zh.; Turganbekova, A.; Akparova, A. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Human leukocyte antigen B27 (HLA-B27) is a molecule of class I major histocompatibility complex. Numerous studies showed an association of the antigen with various types of spondyloarthropathies. The strength of this ...
  • Role of astrocyte aging in the pathogenesis of alzheimer`s disease 
    Imangali, N.; Alimbetov, D.; Tsoy, A.; Saparbayev, S.; Askarova, Sh. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Alzheimer's disease (AD) is the most abundant severe and irreversible neurodegenerative disease in the world that affects people over 65 years old. The major hallmarks of AD pathology are the senile p-amyloid plaques, ...
  • Elevated levels of plasma collagen priple helix repeat-containing (CTHRC1) protein correlates with increased granul ocytopoiesis and higher rheumatoid arthritis disease severity score 
    Myngbay, A.; Bexeitov, Y.; Adilbayeva, A.; Yevstratenko, B. P.; Aitzhanova, R. M.; Otarbayev, N. K.; Adarichev, V.A. (2016-05)
    Monitoring and suppressing activity of the pathological granulating pannus tissue is essential for Rheumatoid Arthritis (RA) management. Synovial joints pain and tissue destruction is a derivative of the pannus activity. ...
  • Establishment of small cell lung cancer cell lines and validation of their growth characteristics 
    Alimbetov, D.; Idrissova, D.; Davis, T.; Kipling, D. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Rapidly metastasizing lung cancer is the top killer in the United States and many other countries. In 2014, there were nearly 224 210 new cases of lung cancer and 159 260 predicted mortality from the disease in the US ...
  • Adipose-derived perivascular stem cell as a source for cell therapy 
    Ogay, V. (2016-05)
    Perivascular stem cells (PSCs) have been isolated from several organs and tissues, including adipose tissue. They have unique features resembling both pericytes and mesenchymal stem cells (MSCs). PSCs as MSCs are capable ...
  • Isolation and characterization of rabbit periosteum-derived mesenchymal stem cells 
    Surumbayeva, A.; Ogay, Vyacheslav (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Periosteum represents a good source for mesenchymal stem cells (MSCs). They have been regarded as a promising therapeutic tool for muscoskeletal regeneration. Periosteum-derived MSCs have higher osteogenic potential in ...
  • Brain-derived neurotrophic factor, neuronal repair and mental health 
    Gard, P. R. (2016-05)
    Brain Derived Neurotrophic Factor (BDNF) is initially synthesized as a 247 amino acid preproBDNF which is cleaved to form a 228 a.a. pro-BDNF and finally 119 a.a. mature BDNF (14 kDa). BDNF is expressed in fibroblasts, ...
  • Recent progress in understanding of hypertension 
    Mutig, K. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Uncontrolled hypertension is associated with increased risk of cardiovascular morbidity and mortality in general population. Renal salt handling is essential for volume regulation and blood pressure control. The ...
  • Erythrocyte ghosts` influence on the phenotypic plasticity of macrophage 
    Khassenbekova, Zh.; Berikkhanova, K.; Gulyayev, A.; Sergazy, Sh.; Yermekbayeva, В.; Kushugulova, A.R.; Omarova, D.; Akhmetova, A.; Nurgozhin, T.; Zhumadilov, Zh. (2016-05)
    Correction of phenotypic plasticity of macrophages for reprogramming inflammatory response is of great interest to modern medicine. To date, there are lots of factors, which can alter macrophages' phenotype to M1 or M2. ...
  • IL-10-1082 A/G pomoter polimorphism is associated with copd 
    Imanbay, A.; Turbekova, Sh.; Akparova, A.Yu.; Abishev, M.T.; Bersimbaev, R. I. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Interleukin-10 is an important immunoregulatory cytokine produced by many cell populations. It inhibits the production of proinflammatory cytokines by macrophages and thus has immunosuppressive effects on T cells, monocytes ...
  • Cancer cells response on the microtubuler-inhibiting drugs 
    Balabiyev, A.; Kakpenova, A.; Kauanova, S.; Vorobjev, I.A. (2016-05)
    Cancer is one of the age-related diseases with detrimental impact on people survival. Improvement of cancer therapies is a major focus of many scientists around the world. Anticancer drugs based on the microtubules ...
  • Assesing the cytokine content of human platelet-rich plasma 
    Masoud, A.; Umbayev, B.; Olzhayev, F.; Idrissova, D.; Shramko, A.; Kaiyrlykyzy, A.; Askarova, Sh. (2016-05)
    Human platelet-rich plasma (PRP) is plasma that is enriched with thrombocytes at a concentration of 1000 * 109 per litre, higher than normal (150 - 350 * 109 per litre). Thrombocytes are known to contain growth factors ...
  • Deep brain stimulation for neurodegenerative diseases 
    Shashkinl, Ch.; Akshulakovl, S.; Makhambetovl, Y.; Shpekovl, A.; Dzhamantaeval, B.; Akhmetzhanovl, V. (2016-05)
    Neurodegenerative diseases (ND) with movement and cognitive disorders are very complicated diseases to treat. Sometimes medical treatment is not successful or results in unpleasant complications. Nowadays neurosurgical ...