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Browsing Research Institute of Biosensors Technology by Subject "Research Subject Categories::NATURAL SCIENCES"

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Browsing Research Institute of Biosensors Technology by Subject "Research Subject Categories::NATURAL SCIENCES"

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  • Insight into DNA substrate specificity of PARP1-catalysed DNA poly(ADP-ribosyl)ation 
    Matkarimov, Bakhyt T.; Matta, Elie; Kiribayeva, Assel; Khassenov, Bekbolat; Ishchenko, Alexander A. (Springer Nature, 2020-02-28)
    DNA-dependent poly(ADP-ribose) polymerases (PARPs) PARP1, PARP2 and PARP3 act as DNA break sensors signalling DNA damage. Upon detecting DNA damage, these PARPs use nicotine adenine dinucleotide as a substrate to synthesise ...