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Browsing Center for Life Sciences by Subject "Research Subject Categories::NATURAL SCIENCES"

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  • Insight into DNA substrate specificity of PARP1-catalysed DNA poly(ADP-ribosyl)ation 
    Matkarimov, Bakhyt T.; Matta, Elie; Kiribayeva, Assel; Khassenov, Bekbolat; Ishchenko, Alexander A. (Springer Nature, 2020-02-28)
    DNA-dependent poly(ADP-ribose) polymerases (PARPs) PARP1, PARP2 and PARP3 act as DNA break sensors signalling DNA damage. Upon detecting DNA damage, these PARPs use nicotine adenine dinucleotide as a substrate to synthesise ...
  • THE MAJOR SATELLITE DNA FAMILIES OF THE DIPLOID CHENOPODIUM ALBUM AGGREGATE SPECIES: ARGUMENTS FOR AND AGAINST THE “LIBRARY HYPOTHESIS” 
    Belyayev, Alexander; Jandova, Michaela; Josefiova, Jiřina; Kalendar, Ruslan; Mahelka, Va´clav; Manda´k, Bohumil; Krak, Karol (Public Library of Science, 2020-10-27)
    Satellite DNA (satDNA) is one of the major fractions of the eukaryotic nuclear genome. Highly variable satDNA is involved in various genome functions, and a clear link between satellites and phenotypes exists in a wide ...
  • Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage 
    Kozhakhmetov, Samat S.; Zhumadilov, Zhaxybay; Kushugulova, Almagul R.; Bartolomaeus, Hendrik; Balogh, András; Yakoub, Mina; Homann, Susanne; Markó, Lajos; Höges, Sascha; Tsvetkov, Dmitry; Krannich, Alexander; Wundersitz, Sebastian; Avery, Ellen G.; Haase, Nadine; Kräker, Kristin; Hering, Lydia; Maase, Martina; Kusche-Vihrog, Kristina; Grandoch, Maria; Fielitz, Jens; Kempa, Stefan; Gollasch, Maik; Eckardt, Kai-Uwe; Dechend, Ralf; Rump, Lars Christian; Forslund, Sofia K.; Müller, Dominik N.; Stegbauer, Johannes; Wilck, Nicola (Wolters Kluwer Health; American Heart Association, 2018-12-04)
    Arterial hypertension and its organ sequelae show characteristics of T cell–mediated inflammatory diseases. Experimental anti-inflammatory therapies have been shown to ameliorate hypertensive end-organ damage. Recently, ...
  • The study of phenolic compounds of the berries of three species of plants of the genus vaccin-ium, growing in the khanty-mansi autonomous area 
    Белова, Екатерина; Тритэк, Владислав; Шульгау, Зарина; Гуляев, Александр; Кривых, Елена; Коваленко, Людмила; Дренин, Алексей; Ботиров, Эркин (Алтайский государственный университет, 2020)
    Впервые проведено исследование химического состава полифенольных соединений плодов клюквы (Vaccinium oxycoccus L.), черники (Vaccinium myrtillus L.) и брусники (Vaccinium vitis-idaea L.), произрастающих на территории Сургутского ...
  • WHOLE GENOME SEQUENCE DATA OF MYCOBACTERIUM TUBERCULOSIS XDR STRAIN, ISOLATED FROM PATIENT IN KAZAKHSTAN 
    Daniyarov, Asset; Molkenov, Askhat; Rakhimova, Saule; Akhmetova, Ainur; Nurkina, Zhannur; Yerezhepov, Dauren; Chingissova, Lyailya; Bismilda, Venera; Toxanbaeva, Bekzat; Akilzhanova, Ainur; Kozhamkulov, Ulan; Kairov, Ulykbek (Elsevier, 2020-12)
    Drug-resistant tuberculosis (TB) is a major public health problem. Clinical Mycobacterium tuberculosis (MTB) isolate with Extensively drug-resistant tuberculosis (MTB-XDR) profile was subjected to whole-genome sequencing ...