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Browsing Center for Life Sciences by Author "a3d89d16-fc91-42d6-b79e-2c74584ed1d2"
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Taipakova, Sabira; Kuanbay, Aigerim; Saint-Pierre, Christine; Gasparutto, Didier; Baiken, Yeldar; Groisman, Regina; Ishchenko, Alexander A.; Saparbaev, Murat; Bissenbaev, Amangeldy K.
(Frontiers Media, 2020-11-26)
Proteins from the poly(ADP-ribose) polymerase (PARP) family, such as PARP1 and PARP2, use NAD+ as a substrate to catalyze the synthesis of polymeric chains consisting of ADP-ribose units covalently attached to an acceptor ...
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Zarkovic, Gabriella; Belousova, Ekaterina; Talhaoui, Ibtissam; Saint-Pierre, Christine; Kutuzov, Mikhail M.; Matkarimov, Bakhyt; Biard, Denis; Gasparutto, Didier; Lavrik, Olga I.; Ishchenko, Alexander A.
(Oxford University Press, 2018-01)
Poly(ADP-ribose) polymerases (PARPs) act as DNA break sensors and catalyze the synthesis of polymers of ADP-ribose (PAR) covalently attached to acceptor proteins at DNA damage sites. It has been demonstrated that both ...
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