D-serine improves learning and memory in epileptic animals
dc.contributor.author | Tokay, T. | |
dc.contributor.author | Mueller, L. | |
dc.contributor.author | Xie, Y. | |
dc.contributor.author | Kirschstein, T. | |
dc.contributor.author | Beck, H. | |
dc.contributor.author | Koehling, R. | |
dc.date.accessioned | 2016-05-30T09:07:43Z | |
dc.date.available | 2016-05-30T09:07:43Z | |
dc.date.issued | 2016-05 | |
dc.description.abstract | The N-methyl-D-aspartate receptor (NMDAR) is critical for the induction of synaptic plasticity and is essential for many forms of learning and memory. Activation of NMDAR by glutamate requires the presence of D-Serine, which is an endogenous physiological coagonist of the receptor and plays an important role in glutamate mediated NMDAR-dependent synaptic plasticity in the brain. However, the role of D-serine in synaptic plasticity and learning in chronic epilepsy is not known. | ru_RU |
dc.identifier.citation | T. Tokay, L. Mueller, Y. Xie, T. Kirschstein, H. Beck, and R. Koehling. 2016. D-series improves learning and memory in epileptic animals. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1518 | ru_RU |
dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/1518 | |
dc.language.iso | en | ru_RU |
dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
dc.subject | Hippocampus | ru_RU |
dc.subject | astrocytes | ru_RU |
dc.subject | epilepsy | ru_RU |
dc.subject | rat | ru_RU |
dc.subject | D-serine | ru_RU |
dc.title | D-serine improves learning and memory in epileptic animals | ru_RU |
dc.type | Abstract | ru_RU |