Analysis of protector mechanism of probiotics using DNA comet assay

dc.contributor.authorZhulamanova, A.
dc.contributor.authorShakhabayeva, G.
dc.contributor.authorSaduakhasova, S.
dc.contributor.authorKozhakhmetov, S.
dc.contributor.authorKushugulova, A.
dc.date.accessioned2015-10-28T08:50:26Z
dc.date.available2015-10-28T08:50:26Z
dc.date.issued2014
dc.description.abstractEcology affects human organism by causing breaks in DNA and, therefore, induce mutations and malignant cell formation. Comet assay is a quantitative method that allows to measure DNA damage in eukaryotic cells (Liao, McNutt, & Zhu, 2009). This method is widely used in areas, such as human biomonitoring, genotoxicology, and ecology. Comet assay is also called a single-cell gel electrophoresis. Thus, the products of electrophoresis are analyzed under the fluorescent light, which makes it similar to comets. DNA strand breaks are detected by comparing the intensity of the comet tail relative to the head (Collins, 2004). Probiotics containing Lactobacillus rhamnosus were used, as Lactobacilli probiotics were found to be safe and effective against urogenital diseases, food hypersensitivity, and dental caries (Lebeer, Vanderleyden, & De Keersmaeckler, 2008). The aim of the research was to study DNA protector mechanism for three probiotic products, containing L. rhamnosus.ru_RU
dc.identifier.isbn9786018046728
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/553
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectecologyru_RU
dc.subjecthuman organismru_RU
dc.subjectDNAru_RU
dc.subjectcomet assayru_RU
dc.subjecteukaryotic cellsru_RU
dc.subjectbiomonitoringru_RU
dc.subjectgenotoxicologyru_RU
dc.subjectgel electrophoresisru_RU
dc.subjectelectrophoresisru_RU
dc.subjectfluorescent lightru_RU
dc.subjectprobioticsru_RU
dc.titleAnalysis of protector mechanism of probiotics using DNA comet assayru_RU
dc.typeAbstractru_RU

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