REVIEW: DETECTION AND QUANTIFICATION OF PROTEINS IN HUMAN URINE

dc.contributor.authorAitekenov, Sultan
dc.contributor.authorGaipov, Abduzhappar
dc.contributor.authorBukasov, Rostislav
dc.date.accessioned2021-10-20T16:03:09Z
dc.date.available2021-10-20T16:03:09Z
dc.date.issued2021
dc.description.abstractExtensive medical research showed that patients, with high protein concentration in urine, have various kinds of kidney diseases, referred to as proteinuria. Urinary protein biomarkers are useful for diagnosis of many health conditions – kidney and cardio vascular diseases, cancers, diabetes, infections. This review focuses on the instrumental quantification (electrophoresis, chromatography, immunoassays, mass spectrometry, fluorescence spectroscopy, the infrared spectroscopy, and Raman spectroscopy) of proteins (the most of all albumin) in human urine matrix. Different techniques provide unique information on what constituents of the urine are. Due to complex nature of urine, a separation step by electrophoresis or chromatography are often used for proteomics study of urine.en_US
dc.identifier.citationAitekenov, S., Gaipov, A., & Bukasov, R. (2021). Review: Detection and quantification of proteins in human urine. Talanta, 223(Pt 1), 121718. https://doi.org/10.1016/j.talanta.2020.121718en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/5868
dc.language.isoenen_US
dc.publisherTalantaen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectUrine proteomicsen_US
dc.subjectBiomarkersen_US
dc.subjectHuman serum albuminen_US
dc.subjectImmunoassaysen_US
dc.subjectMass spectrometryen_US
dc.subjectFluorescence spectroscopyen_US
dc.titleREVIEW: DETECTION AND QUANTIFICATION OF PROTEINS IN HUMAN URINEen_US
dc.typeArticleen_US
workflow.import.sourcescience

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