Genetic homongeneity and major histocompatibility complex haplotyping of white mice

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dc.contributor.authorSydykova, K.
dc.contributor.authorSadykov, M.
dc.contributor.authorZhailauova, A.
dc.contributor.authorAdilbayeva, A.
dc.contributor.authorMyngbay, A.
dc.contributor.authorAdarichev, V. A.
dc.date.accessioned2015-10-21T09:08:58Z
dc.date.available2015-10-21T09:08:58Z
dc.date.issued2014
dc.description.abstractInbred murine strains are generated to insure genetic homogeneity and uniqueness and define immune characteristics, like major histocompatibility complex (MHC) haplotype, of the experimental model. Maintaining of the perfect inbred stock leads to increased level of homozygosity and sometimes encounters a problem of inbreeding depression and consequently deviation from strict inbreeding protocol. Our goals are (i) study genetic homogeneity of mice in the colony, and (ii) haplotyping of H-2 complex (MHC in mice) in this strain.ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/414
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectgenetic homogeneityru_RU
dc.subjecthistocompatibility complexru_RU
dc.subjecthaplotyperu_RU
dc.subjectDNA productru_RU
dc.titleGenetic homongeneity and major histocompatibility complex haplotyping of white miceru_RU
dc.typeAbstractru_RU

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