WHOLE-GENOME SEQUENCING DATA OF KAZAKH INDIVIDUALS

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dc.contributor.authorKairov, Ulykbek
dc.contributor.authorMolkenov, Askhat
dc.contributor.authorRakhimova, Saule
dc.contributor.authorKozhamkulov, Ulan
dc.contributor.authorSharip, Aigul
dc.contributor.authorKarabayev, Daniyar
dc.contributor.authorDaniyarov, Asset
dc.contributor.authorLee, Joseph H.
dc.contributor.authorTerwilliger, Joseph D.
dc.contributor.authorAkilzhanova, Ainur
dc.contributor.authorZhumadilov, Zhaxybay
dc.date.accessioned2021-08-04T09:52:24Z
dc.date.available2021-08-04T09:52:24Z
dc.date.issued2021-02-04
dc.description.abstractObjectives: Kazakhstan is a Central Asian crossroad of European and Asian populations situated along the way of the Great Silk Way. The territory of Kazakhstan has historically been inhabited by nomadic tribes and today is the multi-ethnic country with the dominant Kazakh ethnic group. We sequenced and analyzed the whole-genomes of five ethnic healthy Kazakh individuals with high coverage using next-generation sequencing platform. This whole-genome sequence data of healthy Kazakh individuals can be a valuable reference for biomedical studies investigating disease associations and population-wide genomic studies of ethnically diverse Central Asian region. Data description: Blood samples have been collected from five ethnic healthy Kazakh individuals living in Kazakhstan. The genomic DNA was extracted from blood and sequenced. Sequencing was performed on Illumina HiSeq2000 next-generation sequencing platform. We sequenced and analyzed the whole-genomes of ethnic Kazakh individuals with the coverage ranging from 26 to 32X. Ranging from 98.85 to 99.58% base pairs were totally mapped and aligned on the human reference genome GRCh37 hg19. Het/Hom and Ts/Tv ratios for each whole genome ranged from 1.35 to 1.49 and from 2.07 to 2.08, respectively. Sequencing data are available in the National Center for Biotechnology Information SRA database under the accession number PRJNA374772.en_US
dc.identifier.citationKairov, U., Molkenov, A., Rakhimova, S., Kozhamkulov, U., Sharip, A., Karabayev, D., Daniyarov, A., H.Lee, J., D.Terwilliger, J., Akilzhanova, A., & Zhumadilov, Z. (2021). Whole-genome sequencing data of Kazakh individuals. BMC Research Notes, 14(1). https://doi.org/10.1186/s13104-021-05464-4en_US
dc.identifier.issn1756-0500
dc.identifier.urihttps://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-021-05464-4
dc.identifier.urihttps://doi.org/10.1186/s13104-021-05464-4
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/5655
dc.language.isoenen_US
dc.publisherBioMed Central Ltden_US
dc.relation.ispartofseriesBMC Research Notes;volume 14, Article number: 45 (2021)
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectBioinformatics analysisen_US
dc.subjectBiomedical researchen_US
dc.subjectGenome annotationen_US
dc.subjectKazakh ethnicityen_US
dc.subjectKazakhstanen_US
dc.subjectNext-generation sequencingen_US
dc.subjectPopulation genomicsen_US
dc.subjectWhole genomeen_US
dc.subjectType of access: Open Accessen_US
dc.titleWHOLE-GENOME SEQUENCING DATA OF KAZAKH INDIVIDUALSen_US
dc.typeArticleen_US
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