WHOLE-GENOME SEQUENCING DATA OF KAZAKH INDIVIDUALS
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Date
2021-02-04
Authors
Kairov, Ulykbek
Molkenov, Askhat
Rakhimova, Saule
Kozhamkulov, Ulan
Sharip, Aigul
Karabayev, Daniyar
Daniyarov, Asset
Lee, Joseph H.
Terwilliger, Joseph D.
Akilzhanova, Ainur
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central Ltd
Abstract
Objectives: Kazakhstan is a Central Asian crossroad of European and Asian populations situated along the way of the Great Silk Way. The territory of Kazakhstan has historically been inhabited by nomadic tribes and today is the multi-ethnic country with the dominant Kazakh ethnic group. We sequenced and analyzed the whole-genomes of five ethnic healthy Kazakh individuals with high coverage using next-generation sequencing platform. This whole-genome sequence data of healthy Kazakh individuals can be a valuable reference for biomedical studies investigating disease associations and population-wide genomic studies of ethnically diverse Central Asian region. Data description: Blood samples have been collected from five ethnic healthy Kazakh individuals living in Kazakhstan. The genomic DNA was extracted from blood and sequenced. Sequencing was performed on Illumina HiSeq2000 next-generation sequencing platform. We sequenced and analyzed the whole-genomes of ethnic Kazakh individuals with the coverage ranging from 26 to 32X. Ranging from 98.85 to 99.58% base pairs were totally mapped and aligned on the human reference genome GRCh37 hg19. Het/Hom and Ts/Tv ratios for each whole genome ranged from 1.35 to 1.49 and from 2.07 to 2.08, respectively. Sequencing data are available in the National Center for Biotechnology Information SRA database under the accession number PRJNA374772.
Description
Keywords
Bioinformatics analysis, Biomedical research, Genome annotation, Kazakh ethnicity, Kazakhstan, Next-generation sequencing, Population genomics, Whole genome, Type of access: Open Access
Citation
Kairov, U., Molkenov, A., Rakhimova, S., Kozhamkulov, U., Sharip, A., Karabayev, D., Daniyarov, A., H.Lee, J., D.Terwilliger, J., Akilzhanova, A., & Zhumadilov, Z. (2021). Whole-genome sequencing data of Kazakh individuals. BMC Research Notes, 14(1). https://doi.org/10.1186/s13104-021-05464-4