Transcriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiency

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dc.contributor.authorAdarichev, V. A.
dc.contributor.authorSarkar, S.
dc.contributor.authorKalamov, N.
dc.contributor.authorBrucker, J.
dc.contributor.authorForde, T. S.
dc.contributor.authorShekhani, M.T.
dc.contributor.authorLyons, B.
dc.date.accessioned2015-10-28T09:55:50Z
dc.date.available2015-10-28T09:55:50Z
dc.date.issued2013
dc.description.abstractWe found that Pgis2-congenic mice that carry genetically-deficient copy of C5(Hc) complement component were susceptible to collagen antibody-induced arthritis while inflammation was transient. Using differential gene expression analysis tools, we identified 20 genes whose down/up regulation in Pgis2-congenic mice might rescue C5 complement deficiency or, in a wider sense, rescue the function of the entire Pgis2 locus.ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/560
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectfirst research weekru_RU
dc.subjectarthritisru_RU
dc.subjectscienceru_RU
dc.titleTranscriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiencyru_RU
dc.typeAbstractru_RU

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