Alterations of oncogenes expression in human NK cells in cancer patients
| dc.contributor.author | Amirbekov, A. | |
| dc.contributor.author | Eraliyeva, L. | |
| dc.contributor.author | Zakiryanova, G. | |
| dc.date.accessioned | 2016-05-30T04:33:37Z | |
| dc.date.available | 2016-05-30T04:33:37Z | |
| dc.date.issued | 2016-05 | |
| dc.description.abstract | C-kit/SCF signaling play a key role in regulating NK cell homeostasis, maturation, proliferation and cytotoxicity. C-kit-deficiency in NK results in significant reduction of their, suggesting imperative role fore-kit signaling in NKcell immunobiology. We have recently showed that human NK cells express not only c-kit-receptor, but also both membrane-bound and soluble forms of c-kit ligand - Stem cell factor. The goal of this study was to characterize the c-kit/SCF autocrine loop in peripheral blood NK cells obtained from patients with cancer. | ru_RU |
| dc.identifier.citation | A. Amirbekov, L. Eraliyeva, G. Zakiryanova. 2016. Alterations of oncogenes expression in human NK cells in cancer patients. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1499 | ru_RU |
| dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/1499 | |
| dc.language.iso | en | ru_RU |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
| dc.subject | NK cells | ru_RU |
| dc.subject | c-Kit | ru_RU |
| dc.subject | SCF | ru_RU |
| dc.subject | c-Myc | ru_RU |
| dc.subject | STAT3 | ru_RU |
| dc.title | Alterations of oncogenes expression in human NK cells in cancer patients | ru_RU |
| dc.type | Abstract | ru_RU |