HISTORY OF ENDOMETRIOSIS IS INDEPENDENTLY ASSOCIATED WITH AN INCREASED RISK OF OVARIAN CANCER

dc.contributor.authorSarría-Santamera, Antonio
dc.contributor.authorKhamitova, Zaukiya
dc.contributor.authorGusmanov, Arnur
dc.contributor.authorTerzic, Milan
dc.contributor.authorPolo-Santos, Mar
dc.contributor.authorOrtega, Miguel A.
dc.contributor.authorAsúnsolo, Angel
dc.date.accessioned2023-04-27T05:41:15Z
dc.date.available2023-04-27T05:41:15Z
dc.date.issued2022
dc.description.abstractEndometriosis is a complex gynecologic disorder that has been associated with a higher risk of ovarian cancer. The purpose of this work is to determine to what extent a history of endometriosis is a risk factor for ovarian cancer in a Spanish population. Methods: A retrospective case–control study was conducted using de-identified data from the Spanish National Health System’s “Primary Care Clinical Database” and “Hospital Minimum Basic Data Set” for the period 2013–2017. Multiple logistics regression analysis was conducted to determine associations between ovarian cancer and endometriosis controlled by sociodemographic characteristics and comorbidities. Results: Data from 608,980 women were analyzed, with 4505 presenting ovarian cancer. Endometriosis patients were shown to have a 2.66-fold increased risk of ovarian cancer when compared to those who did not have endometriosis by controlling age and other relevant comorbidities. Conclusions: This case–control study based on clinical administrative data has found that a history of endometriosis is independently associated with an increased risk of ovarian cancer. More research is needed to determine if a history of endometriosis affects survival results in ovarian cancer patients.en_US
dc.identifier.citationSarría-Santamera, A., Khamitova, Z., Gusmanov, A., Terzic, M., Polo-Santos, M., Ortega, M. A., & Asúnsolo, Á. (2022). History of Endometriosis Is Independently Associated with an Increased Risk of Ovarian Cancer. Journal of Personalized Medicine, 12(8), 1337. https://doi.org/10.3390/jpm12081337en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/7043
dc.language.isoenen_US
dc.publisherJournal of Personalized Medicineen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectType of access: Open Accessen_US
dc.subjectendometriosisen_US
dc.subjectovarian canceren_US
dc.subjectsociodemographic characteristicsen_US
dc.subjectrisken_US
dc.titleHISTORY OF ENDOMETRIOSIS IS INDEPENDENTLY ASSOCIATED WITH AN INCREASED RISK OF OVARIAN CANCERen_US
dc.typeArticleen_US
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