CLONOGENIC CAPACITY OF CANCER CELLS AFTER MITOTIC SLIPPAGE
| dc.contributor.author | Yeskendirova, Raushan | |
| dc.date.accessioned | 2023-06-05T08:09:12Z | |
| dc.date.available | 2023-06-05T08:09:12Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Microtubules are a vital part of eukaryotic cells that assist in many processes, such as cell motility, spreading, intracellular transport, and mitosis. They are polymer structures that comprise α- and β-tubulin heterodimers and form 13 protofilaments. Each α and β monomer has a GTP-binding site. However, GTP bound to the α-tubulin is trapped and never hydrolyzed, whereas GTP on the β-tubulin could be either in GTP- or GDP-bound form and, thus, is exchangeable. The hydrolysis of GTP on the β-tubulin site impacts the microtubular dynamics. | en_US |
| dc.identifier.citation | Yeskendirova, R. (2023). Clonogenic capacity of cancer cells after mitotic slippage. School of Sciences and Humanities | en_US |
| dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/7182 | |
| dc.language.iso | en | en_US |
| dc.publisher | School of Sciences and Humanities | en_US |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
| dc.subject | Type of access: Open Access | en_US |
| dc.subject | cancer cells | en_US |
| dc.subject | mitotic slippage | en_US |
| dc.subject | Clonogenic capacity | en_US |
| dc.title | CLONOGENIC CAPACITY OF CANCER CELLS AFTER MITOTIC SLIPPAGE | en_US |
| dc.type | Master's thesis | en_US |
| workflow.import.source | science |
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