Browsing School of Sciences and Humanities by Subject "mammalian target of rapamycin"

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Formation of mammalian preribosomes proceeds from intermediate to composed state during ribosome maturation

Abetov, Danysh; Kiyan, V.; Zhylkibayev, A.; Sarbassova, Dilara; Alybayev, Sanzhar; Spooner, Eric; Song, Min Sup; Bersimbaev, R. I.; Sarbassov, D. (JOURNAL OF BIOLOGICAL CHEMISTRY, 2019-07-12)

In eukaryotes, ribosome assembly is a rate-limiting step in ribosomal biogenesis that takes place in a distinctive subnuclear organelle, the nucleolus. How ribosomes get assembled at the nucleolar site by forming initial ...