Development of non-integrative autonomously replicating vectors for epigenetic reprogramming of somatic cells

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dc.contributor.author	Shustov, A. V.
dc.contributor.author	Baltabekova, A.Zh.
dc.contributor.author	Evtyhova, L.B.
dc.contributor.author	Ramankulov, Ye.M.
dc.date.accessioned	2015-10-28T11:07:05Z
dc.date.available	2015-10-28T11:07:05Z
dc.date.issued	2013
dc.identifier.uri	http://nur.nu.edu.kz/handle/123456789/569
dc.description.abstract	The idea of the project is to utilize the genome of well-described alphavirus VEE as vector for delivery and expression of the human pluripotency factors used for epigenetic reprogramming of somatic cells, namely Nanog, Oct3/4, Sox2, Klf4, and c-Myc. To date, no non-integrative viral vectors for epigenetic reprogramming of cells are available, except for the system utilizing the genome of negative strand RNA-virus, Sendai paramyxovirus.	ru_RU
dc.language.iso	en	ru_RU
dc.publisher	Nazarbayev University	ru_RU
dc.subject	first research week	ru_RU
dc.subject	cells	ru_RU
dc.subject	induced pluripotent stem cells	ru_RU
dc.subject	viruses	ru_RU
dc.title	Development of non-integrative autonomously replicating vectors for epigenetic reprogramming of somatic cells	ru_RU
dc.type	Abstract	ru_RU