Аннотации:
Introduction
Infertility is a problem that affects millions of people worldwide. The aim of this study was to
assess the effect of stress, depression and anxiety on the IVF outcomes in Kazakhstan.
Methods
The prospective cohort study was performed using questionnaires to assess psychological
distress in 304 infertile female in three different cities in Kazakhstan.
Results
The average age of participants was 33.7 years with infertility duration of 5.9 years. Regarding stress, depression and anxiety we found that more than 80% of all respondents had
CES-D score higher than 16, indicating that they are at risk of developing clinical depression. On average, FPI subscales’ scores, global stress score and anxiety scale (STAI-S and
STAI-T) scores were statistically significantly higher among not pregnant women than pregnant women. Similarly, in simple logistic regression analysis all FPI subscales scores, global
stress scale score and anxiety scales’ scores were negatively associated with clinical
pregnancy.
Conclusion
Rates of stress, anxiety and depression among IVF patients are higher than in general population. If the level of infertility-related stress is higher, IVF success rate is lower. Findings of
our study indicate the need for the specific psychological interventions for all infertility
women, to improve IVF success rate.