Browsing Theses and Dissertations by Subject "DNA"

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Oral administration of chitosan/DNA nanoparticles containing DNA coding for FVIII and FC IgG fragment or IL-10 for the modulation of immune responses to FVIII in hemophilia mice

Yerkesh, Zhadyra (Nazarbayev University School of Science and Technology, 2016)

Hemophilia A is an X-linked bleeding disorder, which occurs due to deficiency of clotting protein FVIII. Current treatment involves regular lifelong infusion of recombinant or plasma-derived FVIII protein, which is ...