Abstract:
Cell therapy using stem cells is a promising strategy for the treatment of ischemic
diseases, nevertheless low viability of implanted cells, is one of the main problems limiting stem cell
therapy. In addition, there is a risk of proliferation of the transformed cells in mesenchymal stem cells
carrying properties of cancer stem cells. Using conditioned media from stem cells instead of stem cell
themselves avoids the risks that may arise with the direct use of stem cells. Conditioned media from
various stem cells contains a different number of cytokines and growth factors, necessary for the natural
process of new vessel formation.