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Browsing Biology by Type "Master's thesis"

Now showing items 1-8 of 8

Application of advanced molecular techniques for analyzing phytoplankton population in Burabay National Nature Park Resort

Sarsembekova, Assel (Nazarbayev University School of Science and Technology, 2016)

In this work, the molecular techniques as DNA extraction, DNA quantification, PCR analysis were optimized and subsequent sequencing was performed on MiSeq platform (Illumina, USA). We aimed to apply molecular methods to ...
Co-expression of FVIII with human IGG FC Fragment or mouse IL-10 in encapsulated G8 myoblast cells as a potential treatment of hemophilia A

Kanketayeva, Zhansaya (Nazarbayev University School of Science and Technology, 2016)

In this master thesis study we have shown that recombination G8 myoblasts, encapsulated in alginate-PLL microcapsules can successfully secrete detectable levels of both Fc and IL-10 out of the capsules and sustain good ...
Concentration dependent mitostatic effect and inhibition of cell motibility by different tubulin binding drugs-comparative study

Balabiyev, Arnat (Nazarbayev University School of Science and Technology, 2016)

Here, we demonstrate the comparative effects of nocodazole, taxol and vinorelbine on mitotic progression and cell motility using mouse fibroblasts and three cancer cell lines
Development of flow cytometry and microscopy techniques to monitor freshwater phytoplankton communities in Kazakhstani lakes

Dashkova, Veronika (Nazarbayev University School of Science and Technology, 2016)

In this project, we tested an approach based on separating fluorescent viability and metabolic dyes between different excitation lasers in order to reach minimal spectral overlap with the autofluorescent signal using flow ...
Migration characteristics of cancer cells grown in embryonic microenvironment and under antiviral agents

Karapina, Orynbassar (Nazarbayev University School of Science and Technology, 2016)

This study describes a method for investigating reprogramming of cancer cells using chicken embryo extract and dimishing cancer cell progressing with acyclovir and it was used as innovative approach to address whether ...
Morphometric characteristics of cancer cells grown in embryonic microenvironment and under antiviral treatment

Shaimerdenova, Madina (Nazarbayev University School of Science and Technology, 2016)

We describe here that both embryonic microenvironment treatment and antiviral treatment have the potential to serve as effective factors in changing morphometric characteristics of two highly aggressive cancer cell lines, ...
Oral administration of chitosan/DNA nanoparticles containing DNA coding for FVIII and FC IgG fragment or IL-10 for the modulation of immune responses to FVIII in hemophilia mice

Yerkesh, Zhadyra (Nazarbayev University School of Science and Technology, 2016)

Hemophilia A is an X-linked bleeding disorder, which occurs due to deficiency of clotting protein FVIII. Current treatment involves regular lifelong infusion of recombinant or plasma-derived FVIII protein, which is ...
Role of astrocyte aging in the pathogenesis of Alzheimer`s disease

Imangali, Nurgul (Nazarbayev University School of Science and Technology, 2016)

In this study we presented in vitro model for replicative senescence of primary human astrocytes isolated from fetal brains