Система будет остановлена для регулярного обслуживания. Пожалуйста, сохраните рабочие данные и выйдите из системы.
Атауы бойынша Biology көру
-
Zou, Fang; Schafer, Nadja; Palesch, David; Brucken, Ruth; Beck, Alexander; Sienczyk, Marcin; Kalbacher, Hubert; Sun, ZiLin; Boehm, Bernhard O.; Burster, Timo
(PLoS ONE, 2011-08-05)
Autoantigenic peptides resulting from self-proteins such as proinsulin are important players in the development of type 1
diabetes mellitus (T1D). Self-proteins can be processed by cathepsins (Cats) within endocytic ...
-
Ibragimova, Nazgul; Zhanzak, Zhuldyz; Meyerbekova, Aizhan; Xie, Yingqiu
(European Urology, 2018-01-01)
Egger et al performed a 10-yr cohort study among 52–79-yr-old men diagnosed with low-risk localized prostate cancer. The objective of this research was to test permanent psychological and quality-of-life effects after ...
-
Kim, Yevgeniy; Kim, Aleksei; Sharip, Ainur; Sharip, Aigul; Jiang, Juhong; Yang, Qing; Xie, Yingqiu
(International Journal of Biological Sciences, 2017-02-17)
One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating ...
-
Imangali, Nurgul
(Nazarbayev University School of Science and Technology, 2016)
In this study we presented in vitro model for replicative senescence of primary human astrocytes isolated from fetal brains
-
Zeng, Zhengyang; Zhang, Qian; Hong, Wei; Xie, Yingqiu; Liu, Yun; Li, Wenxin; Wu, Yingliang; Cao, Zhijian
(MDPI, 2016-04-27)
Hepatitis B virus (HBV) infection is a major worldwide health problem which can cause
acute and chronic hepatitis and can significantly increase the risk of liver cirrhosis and primary
hepatocellular carcinoma (HCC). ...
-
Zhubanchaliyev, Altynbek; Temirbekuly, Aibar; Kongrtay, Kuralay; Wanshura, Leah C.; Kunz, Jeannette
(Frontiers in Pharmacology, 2016-12-01)
Liver fibrosis is the result of a deregulated wound healing process characterized by the excessive deposition of extracellular matrix. Hepatic stellate cells (HSCs), which are activated in response to liver injury, are the ...
-
Kozhakhmetova, A; Gillespie, KM
(Methods in Molecular Biology, 2016)
Type 1 diabetes, resulting from the autoimmune destruction of insulin producing islet beta cells is caused by genetic and environmental determinants. Recent studies agree that counterintuitively, the major genetic ...