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Browsing NU Research Week - II by Author "Askarova, Sholpan"

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Browsing NU Research Week - II by Author "Askarova, Sholpan"

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  • Age-realted dementia in Kazahstan: adaptation of the 10/66 dementia research group population -based study protocol 
    Kaiyrlykyzy, A.; Adambekov, Sh.; Alimbetov, D.; Askarova, Sholpan (Nazarbayev University, 2014)
    Background. The prevalence of dementia is increasing worldwide as the population ages and affects 10 % of the population over 65 years old and 40 % of people over the age of 80.[1] In Kazakhstan, as well as in other ...
  • Altered NR2A/NR2B ratio in hippocampus of spatial learning-impaired aged rats 
    Tokay, T.; Rehberg, M.; Kirschstein, T.; Rohde, M.; Mueller, L.; Askarova, Sholpan; Kohling, R.; Zhumadilov, Z. (Nazarbayev University, 2014)
    The activation of the N-methyl-D-aspartate receptor (NMDAR) is critical for the induction of synaptic plasticity in the hippocampus. Aging can alter glutamatergic synaptic transmission in the hippocampus, and cognitive ...
  • Differentiation of mesenchymal stem cells into hepatocytes 
    Ualiyeva, S.; Umbayev, B.; Masoud, A.; Askarova, Sholpan (Nazarbayev University, 2014)
    Acute and chronic liver diseases are common in Kazakhstan and other countries. These diseases are known to cause significant disability and death. In many cases, liver transplantation is the last resort for patients with ...
  • Isolation of primary human hepatocytes from cirrhotic liver 
    Ualiyeva, S.; Umbayev, B.; Donbay, A.; Askarova, Sholpan (Nazarbayev University, 2014)
    Chronic degenerative liver diseases are among most complex social, clinical and epidemiological health problems worldwide. This is due to the steady increase in the incidence and mortality of patients with this pathology. ...
  • Research on the bio-distribution of interferon gamma-containing pharmacocytes 
    Ibrasheva, D.; Idrissova, D.; Umbayev, B.; Masoud, A.; Askarova, Sholpan (Nazarbayev University, 2014)
    Viral hepatitis B and C- is a widespread infectious disease of the liver and is a potential threat to human life. Treatment of HCV and HBV requires prolonged (parenteral or oral) administration of antiviral and ...
  • Role of ROS in AB42 mediated cell surface P-selectin expression and actin polymerization 
    Tsoy, A.; Askarova, Sholpan; Shalakhmetova, T.; Umbayev, B.; Adambekov, S.; Zhumadilov, Z. (Nazarbayev University, 2014)
    Blood-brain barrier dysfunction plays an important role in the onset and progression of Alzheimer's disease (AD). In the AD brains an increased deposition of A(3 in the cerebral vasculature has been found to correlate ...