Migration characteristics of cell grown in embryonic microenvironment and under antiviral agents

Abstract

Cancer metastasis is a crucial process of spread of cancer cells from the origin of tumor lesion to the tissues and other organs beyond, where new tumor lesions are formed which might be a single kick of event that may bring to the death of most of cancer suffering patients. It is known that there are various characteristics between aggressive cancer cells and embryonic progenitors, which gave rise to the theory of "embryonic rest" and suggested possibility of presence of dormant embryonic remnants in differentiated tissues that may have direct link to the generation of cancer lesions when these remnants get activated in the differentiated tissue microenvironments. This concept was a foundation to use of embryonic microenvironment as a treating agent against cancer cells. There are many factors like bad died, use of tobacco, genetic factors and viral infections that influence the occurrence of cancer. It is well-known that cancer cells have a long history with viruses, which may give arise to cancer lesions. It is estimated that 15 percent of all worldwide human cancer cases are related to viruses, which represents a major portion of worldwide cancer problems. Thus, it was decided to use of antiviral agent (e.g. Acyclovir) as well as with chicken embryonic extract in cancer cell reprogramming