Browsing 02.National Laboratory Astana by Subject "base excision repair"

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Aberrant DNA glycosylase-initiated repair pathway of free radicals induced DNA damage: implications for age-related diseases and natural aging

Matkarimov, B.; Saparbaev, M. (Biopolymers and Cell. doi: http://dx.doi.org/10.7124/bc.000943, 2017)

Aerobic cellular respiration generates reactive oxygen species (ROS), which can damage macro-molecules including lipids, proteins and DNA. It was proposed that aging is a consequence of accumulation of naturally occurring ...