Browsing 02.National Laboratory Astana by Subject "Xeroderma Pigmentosum group C"

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XPC DEFICIENCY INCREASES RISK OF HEMATOLOGIC MALIGNANCIES THROUGH MUTATOR PHENOTYPE AND CHARACTERISTIC MUTATIONAL SIGNATURE

Yurchenko, Andrey A.; Padioleau, Ismael; Matkarimov, Bakhyt T.; Soulier, Jean; Sarasin, Alain; Nikolaev, Sergey (Nature Research, 2020-11-17)

Recent studies demonstrated a dramatically increased risk of leukemia in patients with a rare genetic disorder, Xeroderma Pigmentosum group C (XP-C), characterized by constitutive deficiency of global genome nucleotide ...