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Browsing 02.National Laboratory Astana by Subject "Type of access: Open Access"

Browsing 02.National Laboratory Astana by Subject "Type of access: Open Access"

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  • GENETIC STRUCTURE, DIFFERENTIATION AND ORIGINALITY OF PINUS SYLVESTRIS L. POPULATIONS IN THE EAST OF THE EAST EUROPEAN PLAIN 
    Vasilyeva, Yulia; Chertov, Nikita; Nechaeva, Yulia; Sboeva, Yana; Pystogova, Nina; Boronnikova, Svetlana; Kalendar, Ruslan (Forests, 2021-07-28)
    In order to carry out activities aimed at conservation and rational use of forest resources; it is necessary to study the main forest-forming plant species in detail. Scots pine (Pinus sylvestris L., Pinaceae) is mainly ...
  • GENOMIC ANALYSIS OF MULTIDRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS STRAINS FROM PATIENTS IN KAZAKHSTAN 
    Daniyarov, Asset; Molkenov, Askhat; Rakhimova, Saule; Akhmetova, Ainur; Yerezhepov, Dauren; Chingissova, Lyailya; Bismilda, Venera; Toksanbayeva, Bekzat; Rakisheva, Anar; Akilzhanova, Ainur; Kozhamkulov, Ulan; Kairov, Ulykbek (Frontiers in Genetics, 2021-11-09)
    Tuberculosis (TB) is an infectious disease that remains an essential public health problem in many countries. Despite decreasing numbers of new cases worldwide, the incidence of antibiotic-resistant forms (multidrug ...
  • GUT MODULATION OF DYSBIOSIS INDUCED BY DEXTRAN SULFATE SODIUM 
    Kozhakhmetov, Samat S.; Babenko, Dmitriy; Kozhakhmetova, Saniya; Tuyakova, Altynay; Nurgaziyev, Madiyar; Nurgozhina, Ayaulym; Muhanbetganov, Nurislam; Chulenbayeva, Laura; Sergazy, Shynggys; Gulyayev, Alexander; Tanabayev, Baimakhan; Saliev, Timur; Kushugulova, Almagul R. (Elsevier Ltd, 2021-06-08)
    Inflammatory bowel disease is one of the serious burdens of clinical medicine and healthcare. This study investigated the potential of a biological product based on mare's milk and metabolites of symbiotic microflora for ...
  • HIGHLY PATHOGENIC AVIAN INFLUENZA VIRUS OF THE A/H5N8 SUBTYPE, CLADE 2.3.4.4B, CAUSED OUTBREAKS IN KAZAKHSTAN IN 2020 
    Amirgazin, Asylulan; Shevtsov, Alexandr; Karibayev, Talgat; Berdikulov, Maxat; Kozhakhmetova, Tamila; Syzdykova, Laura; Ramankulov, Yerlan; Shustov, Alexandr V. (PeerJ, 2022)
    Background. Large poultry die-offs happened in Kazakhstan during autumn of 2020. The birds’ disease appeared to be avian influenza. Northern Kazakhstan was hit first and then the disease propagated across the country ...
  • HIGH SARS-COV-2 SEROPREVALENCE IN KARAGANDA, KAZAKHSTAN BEFORE THE LAUNCH OF COVID-19 VACCINATION 
    Kadyrova, Irina; Yegorov, Sergey; Negmetzhanov, Baurzhan; Kolesnikova, Yevgeniya; Kolesnichenko, Svetlana; Korshukov, Ilya; Akhmaltdinova, Lyudmila; Vazenmiller, Dmitriy; Stupina, Yelena; Kabildina, Naylya; Ashimova, Assem; Raimbekova, Aigul; Turmukhambetova, Anar; Miller, Matthew S.; Hortelano, Gonzalo; Babenko, Dmitriy (PLOS ONE, 2022-07-27)
    COVID-19 exposure in Central Asia appears underestimated and SARS-CoV-2 seroprevalence data are urgently needed to inform ongoing vaccination efforts and other strategies to mitigate the regional pandemic. Here, in a ...
  • IMPROVEMENT OF NEUROLOGICAL FUNCTION IN RATS WITH ISCHEMIC STROKE BY ADIPOSEDERIVED PERICYTES 
    Ogay, Vyacheslav; Kumasheva, Venera; Li, Yelena; Mukhlis, Sholpan; Sekenova, Aliya; Olzhayev, Farkhad; Tsoy, Andrey; Umbayev, Baurzhan; Askarova, Sholpan; Shpekov, Azat; Kaliyev, Assylbek; Zhetpisbayev, Berik; Makhambetov, Yerbol; Akshulakov, Serik; Saparov, Arman; Ramankulov, Yerlan (SAGE Publications, 2020-09-04)
    Pericytes possess high multipotent features and cell plasticity, and produce angiogenic and neurotrophic factors that indicate their high regenerative potential. The aim of this study was to investigate whether transplantation ...
  • AN INTEGRATED APPROACH TO UNDERSTANDING RF VACUUM ARCS 
    Norem, J.; Insepov, Z.; Hassanein, A. (Nature Research, 2021-01-27)
    Although used in the design and costing of large projects such as linear colliders and fusion tokamaks, the theory of vacuum arcs and gradient limits is not well understood. Almost 120 years after the isolation of vacuum ...
  • IS THERE AN ADVANTAGEOUS ARRANGEMENT OF AROMATIC RESIDUES IN PROTEINS? STATISTICAL ANALYSIS OF AROMATIC INTERACTIONS IN GLOBULAR PROTEINS 
    Lobanov, Mikhail Yu.; Pereyaslavets, Leonid B.; Likhachev, Ilya V.; Matkarimov, Bakhyt; Galzitskaya, Oxana V. (Computational and Structural Biotechnology Journal, 2021)
    The aim of this study was to evaluate the favorability of different conformations of aromatic residues in proteins by analysing the occurrence of particular conformations. The clustering of protein structures from the ...
  • MECHANISTIC INSIGHT INTO THE ROLE OF POLY(ADP-RIBOSYL)ATION IN DNA TOPOLOGY MODULATION AND RESPONSE TO DNA DAMAGE 
    Matkarimov, Bakhyt T.; Zharkov, Dmitry O.; Saparbaev, Murat K. (Mutagenesis, 2010)
    Genotoxic stress generates single- and double-strand DNA breaks either through direct damage by reactive oxygen species or as intermediates of DNA repair. Failure to detect and repair DNA strand breaks leads to deleterious ...
  • MESENCHYMAL STEM CELLS COATED WITH SYNTHETIC BONE-TARGETING POLYMERS ENHANCE OSTEOPOROTIC BONE FRACTURE REGENERATION 
    Safarova, Yuliya; Olzhayev, Farkhad; Umbayev, Bauyrzhan; Tsoy, Andrey; Hortelano, Gonzalo; Tokay, Tursonjan; Murata, Hironobu; Russell, Alan; Askarova, Sholpan (MDPI AG, 2020-10-12)
    Osteoporosis is a progressive skeletal disease characterized by reduced bone density leading to bone fragility and an elevated risk of bone fractures. In osteoporotic conditions, decrease in bone density happens due to the ...
  • A MINI-REVIEW ON RECENT DEVELOPMENTS IN ANTI-ICING METHODS 
    Kenzhebayeva, Adelya; Bakbolat, Baglan; Sultanov, Fail; Daulbayev, Chingis; Mansurov, Zulkhair (MDPI, 2021-11-27)
    An aggressive impact of the formed ice on the surface of man-made objects can ultimately lead to serious consequences in their work. When icing occurs, the quality and characteristics of equipment, instruments, and building ...
  • MODIFIED “ALLELE-SPECIFIC QPCR” METHOD FOR SNP GENOTYPING BASED ON FRET 
    Kalendar, Ruslan; Baidyussen, Akmaral; Serikbay, Dauren; Zotova, Lyudmila; Khassanova, Gulmira; Kuzbakova, Marzhan; Jatayev, Satyvaldy; Hu, Yin-Gang; Schramm, Carly; Anderson, Peter A.; Jenkins, Colin L. D.; Soole, Kathleen L.; Shavrukov, Yuri (Frontiers in Plant Science, 2022)
    The proposed method is a modified and improved version of the existing “Allele-specific q-PCR” (ASQ) method for genotyping of single nucleotide polymorphism (SNP) based on fluorescence resonance energy transfer (FRET). ...
  • ONION-STRUCTURED SI ANODE CONSTRUCTED WITH COATING BY LI4TI5O12 AND CYCLIZED-POLYACRYLONITRILE FOR LITHIUM-ION BATTERIES 
    Nurpeissova, Arailym; Mukanova, Aliya; Kalimuldina, Gulnur; Umirov, Nurzhan; Kim, Sung-Soo; Bakenov, Zhumabay (Nanomaterials, 2020-10-10)
    Low dimensional Si-based materials are very promising anode candidates for the next-generation lithium-ion batteries. However, to satisfy the ever-increasing demand in more powerful energy storage devices, electrodes based ...
  • PALINDROMIC SEQUENCE-TARGETED (PST) PCR, VERSION 2: AN ADVANCED METHOD FOR HIGH-THROUGHPUT TARGETED GENE CHARACTERIZATION AND TRANSPOSON DISPLAY 
    Kalendar, Ruslan; Shustov, Alexandr V.; Schulman, Alan H. (Frontiers Media S.A., 2021-06-22)
    Genome walking (GW), a strategy for capturing previously unsequenced DNA fragments that are in proximity to a known sequence tag, is currently predominantly based on PCR. Recently developed PCR-based methods allow for ...
  • PHOTOACTIVE TUNGSTEN-OXIDE NANOMATERIALS FOR WATER-SPLITTING 
    Shabdan, Yerkin; Markhabayeva, Aiymkul; Bakranov, Nurlan; Nuraje, Nurxat (MDPI, 2020-09-18)
    This review focuses on tungsten oxide (WO3) and its nanocomposites as photoactive nanomaterials for photoelectrochemical cell (PEC) applications since it possesses exceptional properties such as photostability, high ...
  • PHOTO CROSSLINKED LIGNIN/PAN ELECTROSPUN SEPARATOR FOR SAFE LITHIUM ION BATTERIES 
    Yerkinbekova, Yerkezhan; Kalybekkyzy, Sandugash; Tolganbek, Nurbol; Kahraman, Memet Vezir; Bakenov, Zhumabay; Mentbayeva, Almagul (Scientific Reports, 2022)
    A novel crosslinked electrospun nanofibrous membrane with maleated lignin (ML) and poly(acrylonitrile) (PAN) is presented as a separator for lithium-ion batteries (LIBs). Alkali lignin was treated with an esterification ...
  • PHYSICAL PROPERTIES OF CARBON NANOWALLS SYNTHESIZED BY THE ICP-PECVD METHOD VS. THE GROWTH TIME 
    Yerlanuly, Yerassyl; Zhumadilov, Rakhymzhan; Nemkayeva, Renata; Uzakbaiuly, Berik; Beisenbayev, Almaz R.; Bakenov, Zhumabay; Ramazanov, Tlekkabul (Scientific Reports, 2021-09-29)
    Investigation of the physical properties of carbon nanowall (CNW) flms is carried out in correlation with the growth time. The structural, electronic, optical and electrical properties of CNW flms are investigated using ...
  • POLYPHENOLS AS CALORIC-RESTRICTION MIMETICS AND AUTOPHAGY INDUCERS IN AGING RESEARCH 
    Yessenkyzy, Assylzhan; Saliev, Timur; Zhanaliyeva, Marina; Masoud, Abdul-Razak; Umbayev, Bauyrzhan; Sergazy, Shynggys; Krivykh, Elena; Gulyayev, Alexander; Nurgozhin, Talgat (MDPI, 2020-05-08)
    It has been thought that caloric restriction favors longevity and healthy aging where autophagy plays a vital role. However, autophagy decreases during aging and that can lead to the development of aging-associated diseases ...
  • PROMOTING POLYSULFIDES REDOX CONVERSION BY SULFUR-DEFICIENT ZNS1 X HOLLOW POLYHEDRONS FOR LITHIUM-SULFUR BATTERIES 
    Gao, Wanjie; Jin, Qianwen; Liu, Yanyu; Zhang, Yongguang; Wang, Xin; Bakenov, Zhumabay (Materials & Design, 2021-08-21)
    Lithium-sulfur (Li-S) batteries are deemed as the attractive systems for high-energy storage. However, the polysulfides shuttling with slow redox kinetics has seriously hindered their practical applications. Herein, ...
  • RE-SEARCHER: GUI-BASED BIOINFORMATICS TOOL FOR SIMPLIFIED GENOMICS DATA MINING OF VCF FILES 
    Karabayev, Daniyar; Molkenov, Askhat; Yerulanuly, Kaiyrgali; Kabimoldayev, Ilyas; Daniyarov, Asset; Sharip, Aigul; Seisenova, Ainur; Zhumadilov, Zhaxybay; Kairov, Ulykbek (PeerJ Inc., 2021-05-03)
    Background. High-throughput sequencing platforms generate a massive amount of high-dimensional genomic datasets that are available for analysis. Modern and user-friendly bioinformatics tools for analysis and interpretation ...