Browsing 02.National Laboratory Astana by Author "fa63d90a-b37a-4dbf-8a8c-0b64283b8d2a"

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IS THERE AN ADVANTAGEOUS ARRANGEMENT OF AROMATIC RESIDUES IN PROTEINS? STATISTICAL ANALYSIS OF AROMATIC INTERACTIONS IN GLOBULAR PROTEINS

Lobanov, Mikhail Yu.; Pereyaslavets, Leonid B.; Likhachev, Ilya V.; Matkarimov, Bakhyt; Galzitskaya, Oxana V. (Computational and Structural Biotechnology Journal, 2021)

The aim of this study was to evaluate the favorability of different conformations of aromatic residues in proteins by analysing the occurrence of particular conformations. The clustering of protein structures from the ...
MECHANISTIC INSIGHT INTO THE ROLE OF POLY(ADP-RIBOSYL)ATION IN DNA TOPOLOGY MODULATION AND RESPONSE TO DNA DAMAGE

Matkarimov, Bakhyt T.; Zharkov, Dmitry O.; Saparbaev, Murat K. (Mutagenesis, 2010)

Genotoxic stress generates single- and double-strand DNA breaks either through direct damage by reactive oxygen species or as intermediates of DNA repair. Failure to detect and repair DNA strand breaks leads to deleterious ...
SPUTNIK-V REACTOGENICITY AND IMMUNOGENICITY IN THE BLOOD AND MUCOSA: A PROSPECTIVE COHORT STUDY

Yegorov, Sergey; Kadyrova, Irina; Negmetzhanov, Baurzhan; Kolesnikova, Yevgeniya; Kolesnichenko, Svetlana; Korshukov, Ilya; Baiken, Yeldar; Matkarimov, Bakhyt; Miller, Matthew S. (Scientific Reports, 2022)

Sputnik-V (Gam-COVID-Vac) is a heterologous, recombinant adenoviral (rAdv) vector-based, COVID- 19 vaccine now used in > 70 countries. Yet there is a shortage of data on this vaccine’s performance in diverse populations. ...