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Browsing 02.National Laboratory Astana by Author "e00c6d65-af6c-416a-9b4c-edd0d2281510"

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DRUG RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS CLINICAL ISOLATES FROM NEW TB CASES IN KAZAKHSTAN

Kozhamkulov, U.; Akhmetova, A.; Rakhimova, S.; Daniyarov, A.; Molkenov, A.; Bismilda, V.; Chingissova, L.; Kairov, U.; Akilzhanova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: Nowadays and worldwide, TB is one of the top 10 causes of death and the leading cause from a single infectious agent. The global incidence of drug-susceptible TB, multidrug-resistant (MDR) and extensively ...
IDENTIFICATION OF KAZAKH SPECIFIC GENOMIC VARIANTS USING COMPARATIVE GENOMICS ANALYSIS

Molkenov, A.; Daniyarov, A.; Sharip, A.; Seisenova, A.; Karabayev, D.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: The modern development of high-performance genomic technologies opens up new possibilities for studying the human genome. Large-scale genomic research generates huge amounts of data, the active development ...
LAUNCH OF Q-SYMPHONY BIOINFORMATICS COMPUTING SYSTEM: A HIGH-PERFORMANCE CLUSTER FOR ANALYSIS OF LARGE-SCALE GENOMIC DATASETS

Molkenov, A.; Daniyarov, A.; Sharip, A.; Seisenova, A.; Karabayev, D.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: One whole human genome, provided by next generation sequencing platforms, in raw format takes 20 to 50 GB. In the course of bioinformatics analysis and data analysis, the data volume increases to 300-500 ...
META-ANALYSIS OF CANCER TRANSCRIPTOMES USING INDEPENDENT COMPONENT ANALYSIS

Seisenova, A.; Sharip, A.; Molkenov, A.; Daniyarov, A.; Karabayev, D.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: Independent Component Analysis (ICA) is a matrix factorization method for data dimension reduction. ICA has been widely applied for the analysis of transcriptomic data for blind separation of biological, ...
MULTIDRUG-RESISTANT TUBERCULOSIS: WHOLE-GENOME SEQUENCING AND BIOINFORMATICS ANALYSIS

Kairov, U.; Kozhamkulov, U.; Daniyarov, A.; Molkenov, A.; Akhmetova, A.; Rakhimova, S.; Akilzhanova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction:Tuberculosis (TB) remains a serious public health threat worldwide. It is estimated that approximately one-third of the world’s population has been infected with multidrug-resistant tuberculosis (MDR-TB), ...
TARGETED NEXT GENERATION SEQUENCING REVEALS NEW INSIGHTS INTO THE GENETIC BASIS OF INHERITED ARRHYTHMIA IN KAZAKHSTANI PATIENTS

Akilzhanova, A.; Guelly, C.; Abilova, Zh.; Rakhimova, S.; Akhmetova, A.; Kairov, U.; Trajanoski, S.; Akilzhanova, G.; Kozhamkulov, U.; Abdrakhmanov, A.; Bekbosynova, M. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction:Ventricular arrhythmias are caused by mutations of ion channels and their interacting proteins. Most arrhythmia syndromes are inherited in an autosomal dominant manner, such that first-degree family members ...
WHOLE TRANSCRIPTOME SEQUENCING ANALYSIS OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA FROM KAZAKHSTAN

Sharip, A.; Rakhimova, S.; Molkenov, A.; Kozhamkulov, U.; Zhukov, Y.; Omarov, M.; Akilzhanova, A.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: Esophageal cancer is the eighth most common cancer worldwide and sixth in Kazakhstan. Esophageal squamous cell carcinoma (ESCC) is the predominant histological subtype of esophageal cancer and diagnosed at ...
WHOLE TRANSCRIPTOME SEQUENCING ANALYSIS OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA FROM KAZAKHSTAN

Sharip, A.; Rakhimova, S.; Molkenov, A.; Kozhamkulov, U.; Zhukov, Y.; Omarov, M.; Akilzhanova, A.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: Esophageal cancer is the sixth most common cancer in Kazakhstan, and usually not detected until it has progressed to an advanced incurable stage. The predominant histological subtype of esophageal cancer ...