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Browsing 02.National Laboratory Astana by Author "2d819391-2712-47be-ac9c-aa13c357b3e9"

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CRITICAL ROLE OF BRAIN-SPECIFIC GANGLIOSIDES IN THE PATHOGENESIS OF TRAUMATIC BRAIN INJURY AND ALZHEIMER’S DISEASE

Ponomarev, Eugene D. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Major brain glycosphingolipids, also called brain gangliosides, are localized within neuronal lipid rafts (NLR) of neuronal axons and synapses and their role in neurodegenerative diseases remains unknown. Here, we compared ...
Neuronal extracellular microRNAs miR-124 and miR-9 mediate cell-cell communication between neurons and microglia

Veremeyko, Tatyana; Kuznetsova, Inna; Dukhinova, Marina; Yung, Amanda; Kopeikina, Ekaterina; Barteneva, Natasha S.; Ponomarev, Eugene D. (National Laboratory Astana, 2019-10-27)

In contrast to peripheral macrophages, microglia in the central nervous system (CNS) exhibit a specific deactivated phenotype; however, it is not clear how this phenotype is maintained. Two alternative hypotheses were ...