Browsing 02.National Laboratory Astana by Author "02473f02-5e40-45e8-8bbc-a653cbec684d"

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Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells

Mu, Xiaodong; Mektepbayeva, Damel; Patel, Stuti; Mahjoub, Adel; Huard, Johnny; Weiss, Kurt (Sarcoma, 2015)

Aldehyde dehydrogenase (ALDH) is a cancer stem cell marker. Retinoic acid has antitumor properties, including the induction of apoptosis and inhibition of proliferation. Retinal, the precursor of retinoic acid, can be ...