DSpace Repository :: Browsing NU Research Week - 2018 by Subject "multidrug-resistant (MDR)"

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Open Access
De Novo Assembly And Bioinformatics Analysis Of M.Tuberculosis Mdr Strains Sequenced On Next-Generation Sequencing Platform
(Nazarbayev University, 2018-10-18) Daniyarov, A.; Kairov, U.; Molkenov, A.; Kozhamkulov, U.; Akhmetova, A.; Akilzhanova, A; Zhumadilov, Zh.
Tuberculosis remains one of the major problems in public health (1). During the last 10 years the tuberculosis incidence and mortality rate in Kazakhstan decreased by 2.4 times and 6 times, respectively. Despite the decreasing rate of incidences in Kazakhstan last years, the rate of multidrug-resistant (MDR) forms is increasing.
Open Access
Whole genome sequencing of m. Tuberculosis strains in kazakhstan reveal genomic variants in genes coding pe/ppe protein family specific for mdr/xdr isolates
(Nazarbayev University, 2018-10-18) Kozhamkulov, U.; Kairov, U.; Molkenov, A.; Steins, M.; Akhmetova, А.; Akilzhanova, A
Worldwide in 2016, around 10.4 million people were diagnosed with TB among which 1.7 million died [1]. Despite the progress in decreasing the global incidence of drug-susceptible TB, multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis in the past decade led to decreased efficiency of chemotherapy. However, the rate of drug-resistant TB increases annually, especially multidrug-resistant TB (MDR TB) [1].