DSpace Repository :: Browsing Materials of conferences and seminars by Author "Adilbayeva, A."

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Open Access
Collagen triple helix repeat containing-1 (cthrc1) regulates the cell migration via focal adhesions in rheumatoid arthritis
(National Laboratory Astana, Nazarbayev University, 2017-09-15) Adilbayeva, A.; Bexeitov, Y.; Gazizova, A.; Myngbay, A.; Kunz, J.; Adarichev, V.
Open Access
Elevated levels of plasma collagen priple helix repeat-containing (CTHRC1) protein correlates with increased granul ocytopoiesis and higher rheumatoid arthritis disease severity score
(2016-05) Myngbay, A.; Bexeitov, Y.; Adilbayeva, A.; Yevstratenko, B. P.; Aitzhanova, R. M.; Otarbayev, N. K.; Adarichev, V.A.
Monitoring and suppressing activity of the pathological granulating pannus tissue is essential for Rheumatoid Arthritis (RA) management. Synovial joints pain and tissue destruction is a derivative of the pannus activity. In a mouse model for RAwe found CTHRC1, a secreted and circulating protein, to be inducible in arthritis and correlated with the disease severity. We performed a clinical investigation to ascertain the role of CTHRC1 in the progression of the disease.