BACKGROUND: The anticancer activity of metformin has been confirmed against several cancer types in vitro and in vivo. However, the underlying mechanisms of metformin in the treatment of cancer are not fully understood. ...

Objectives: Human papillomavirus is themain causative agent for cervical cancer. However, few data are available about HPV prevalence in Kazakhstan. The aims of this study were to genotype HPV DNA in Pap smear samples of ...

Muscular dystrophy is a condition potentially predisposing for cancer; however, currently, only Myotonic dystrophy patients are known to have a higher risk of cancer. Here, we have searched for a link between facioscapulohumeral ...

The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer ...

Cancer relapse and metastasis remain one of the main problems in treatment of breast cancer (BC). A small subset from bulk tumor cells, called breast cancer stem cells (BCSCs), is found to be responsible for cancer initiation, ...

Breast cancer is the most common type of cancer, with over 2.2 million cases reported in 2020. Breast cancer treatment can be highly effective, especially when the disease can be detected at an early stage. Nowadays, ...

Viral infections contribute as a cause of 15–20% of all human cancers. Infection by oncogenic viruses can promote different stages of carcinogenesis. Among many types of HPV, around 15 are linked to cancer. In spite of ...

Current first-line chemotherapy generally consists of cytotoxic agents. While these agents may initially control disease by effectively debulking tumors, the tumors invariably recur due to the ability of cancer stem cells ...

Cervical cancer is a high burden disease worldwide that often results from the infection by the Human Papilloma Virus (HPV). It is one of the most preventable cancers, as vaccines against HPV that can prevent more than 90% ...