CETYLTRIMETHYLAMMONIUM BROMIDE (CTAB)-LOADED SIO2–AG MESOPOROUS NANOCOMPOSITE AS AN EFFICIENT ANTIBACTERIAL AGENT
| dc.contributor.author | Abduraimova, Aiganym | |
| dc.contributor.author | Molkenova, Anara | |
| dc.contributor.author | Duisembekova, Assem | |
| dc.contributor.author | Mulikova, Tomiris | |
| dc.contributor.author | Kanayeva, Damira | |
| dc.contributor.author | Atabaev, Timur Sh. | |
| dc.date.accessioned | 2021-09-15T07:08:19Z | |
| dc.date.available | 2021-09-15T07:08:19Z | |
| dc.date.issued | 2021-02-13 | |
| dc.description.abstract | To date, Ag-based nanomaterials have demonstrated a high potential to overcome antibiotic resistance issues. However, bare Ag nanomaterials are prone to agglomeration in the biological environment, which results in a loss of antibacterial activity over time. Furthermore, it is still challenging to collect small-sized Ag nanomaterials right after the synthesis process. In this study, spherical-shaped Ag nanoparticles (NPs) (~6–10 nm) were attached on the surface of cetyltrimethylammonium bromide (CTAB)-loaded mesoporous silica nanoparticles (MSNs) (~100–110 nm). Antibacterial activity tests suggested that the obtained nanocomposite can be used as a highly efficient antibacterial agent against both Gram-negative and Gram-positive bacterial strains. The minimum inhibitory concentration (MIC) recalculated to pure Ag weight in nanocomposite was found to be ~1.84 µg/mL (for Escherichia coli) and ~0.92 µg/mL (for Staphylococcus aureus)—significantly smaller compared to values reported to date. The improved antibacterial activity of the prepared nanocomposite can be attributed to the even distribution of non-aggregated Ag NPs per volume unit and the presence of CTAB in the nanocomposite pores. | en_US |
| dc.identifier.citation | Abduraimova, A., Molkenova, A., Duisembekova, A., Mulikova, T., Kanayeva, D., & Atabaev, T. S. (2021). Cetyltrimethylammonium Bromide (CTAB)-Loaded SiO2–Ag Mesoporous Nanocomposite as an Efficient Antibacterial Agent. Nanomaterials, 11(2), 477. https://doi.org/10.3390/nano11020477 | en_US |
| dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/5775 | |
| dc.language.iso | en | en_US |
| dc.publisher | Nanomaterials | en_US |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
| dc.subject | Type of access: Open Access | en_US |
| dc.subject | mesoporous silica | en_US |
| dc.subject | silver | en_US |
| dc.subject | nanocomposite | en_US |
| dc.subject | cetyltrimethylammonium bromide | en_US |
| dc.subject | antibacterial activity | en_US |
| dc.title | CETYLTRIMETHYLAMMONIUM BROMIDE (CTAB)-LOADED SIO2–AG MESOPOROUS NANOCOMPOSITE AS AN EFFICIENT ANTIBACTERIAL AGENT | en_US |
| dc.type | Article | en_US |
| workflow.import.source | science |