THE FREQUENT SAMPLING OF WOUND SCRATCH ASSAY REVEALS THE “OPPORTUNITY” WINDOW FOR QUANTITATIVE EVALUATION OF CELL MOTILITY-IMPEDING DRUGS

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dc.contributor.authorKauanova, Sholpan
dc.contributor.authorUrazbayev, Arshat
dc.contributor.authorVorobjev, Ivan
dc.date.accessioned2021-10-06T17:30:09Z
dc.date.available2021-10-06T17:30:09Z
dc.date.issued2021-03-11
dc.description.abstractWound healing assay performed with automated microscopy is widely used in drug testing, cancer cell analysis, and similar approaches. It is easy to perform, and the results are reproducible. However, it is usually used as a semi-quantitative approach because of inefficient image segmentation in transmitted light microscopy. Recently, several algorithms for wound healing quantification were suggested, but none of them was tested on a large dataset...en_US
dc.identifier.citationKauanova S, Urazbayev A and Vorobjev I (2021) The Frequent Sampling of Wound Scratch Assay Reveals the “Opportunity” Window for Quantitative Evaluation of Cell Motility-Impeding Drugs. Front. Cell Dev. Biol. 9:640972. doi: 10.3389/fcell.2021.640972en_US
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/5858
dc.language.isoenen_US
dc.publisherFront. Cell Dev. Biol.en_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectwound healingen_US
dc.subjecthigh-throughputen_US
dc.subjectlabel-free microscopyen_US
dc.subjectlive-cell imagingen_US
dc.subjectsegmentation automationen_US
dc.subjectcell motilityen_US
dc.titleTHE FREQUENT SAMPLING OF WOUND SCRATCH ASSAY REVEALS THE “OPPORTUNITY” WINDOW FOR QUANTITATIVE EVALUATION OF CELL MOTILITY-IMPEDING DRUGSen_US
dc.typeArticleen_US
workflow.import.sourcescience

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