Antiviral Resistance of Splenocytes in Aged Mice

dc.contributor.authorBurster, Timo
dc.date.accessioned2019-11-01T05:18:11Z
dc.date.available2019-11-01T05:18:11Z
dc.date.issued2017-03-30
dc.description.abstractWe compared the susceptibility to viral infection of splenocytes, isolated from young versus old CBA mice, and evaluated the antiviral actions of lactoferrin in splenocytes infected with Encephalomyocarditis virus (EMCV). Recombinant mouse lactoferrin (rmLF) and bovine lactoferrin (bLF) were used. There were no differences in the susceptibility to EMCV infection in the studied age categories. Both types of lactoferrins were protective in young and old mice. The study confirmed the undisturbed viral resistance in old mice and the protective actions of lactoferrin in viral infection. The antiviral action of the homologous mouse lactoferrin was demonstrated for the first time.en_US
dc.identifier.citationZaczyńska, E., Artym, J., Kocięba, M., Burster, T., Kruzel, M., Paprocka, M., & Zimecki, M. (2017). Antiviral Resistance of Splenocytes in Aged Mice. Polish Journal of Microbiology, 66(1), 131-134. https://doi.org/10.5604/17331331.1235002en_US
dc.identifier.otherhttps://doi.org/10.5604/17331331.1235002
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/4275
dc.language.isoenen_US
dc.publisherNazarbayev University School of Sciences and Humanitiesen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.titleAntiviral Resistance of Splenocytes in Aged Miceen_US
dc.typeArticleen_US
workflow.import.sourcescience

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