Anticancer effects of leech extract on breast cancer cells
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Date
2016-05
Authors
Murzakhmetova, S.
Janzakova, D.
Mektepbayeva, D.
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Abstract
Throughout the history of humanity, leech therapy appeared as a procedure
in medicine all over the world. The very first use of leech in human treatment was mentioned
in Eqypt 3500 years ago. In 2004, Food and Drug Administration approved leeches as medical
devices and, nowadays, leeches are used in treatment of diseases, such as hypertension,
varicose ulcer, thrombophlebitis and musculoskeletal diseases. In this experiment we are trying
to see whether the leech saliva extract (LSE) has anti-cancer effects on MCF-7 breast cancer
cells. Several studies were conducted previously that have shown positive effects of LSE on
cancer cells. Warfarin and heparin from the extract are found to have antimetastatic effect.
Experiments on lung tumor cells also indicated inhibitory effect of LSE.
Description
Keywords
cancer, breast cancer, leech, proliferation, viability, soft agar
Citation
S. Murzakhmetova, D. Janzakova, D. Mektepbayeva. 2016. Anticancer effects of leech extract on breast cancer cells. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1500