POLYCAPROLACTONE AND POLYETHYLENE TEREPHTHALATE NANOFIBER GRAFTS FOR ANTERIOR CRUCIATE LIGAMENT TISSUE APPLICATIONS

Loading...
Thumbnail Image

Journal Title

Journal ISSN

Volume Title

Publisher

Nazarbayev University School of Engineering and Digital Sciences

Abstract

The present study hypothesizes that the produced graft from two different polymers (PCL&PET) with aligned-bimodal and unaligned-unimodal fibers can mimic the properties of healthy and injured ACL rabbit tissue, respectively. To observe if the created graft is useful to replicate the conditions for ACL restoration, primary fibroblasts taken from rabbit’s ACL tissue were seeded on two different types of scaffolds: aligned fibers, which represent healthy ACL tissue, and unaligned, which represent injured ACL tissue. After cell seeding, the evaluation of cell proliferation and DNA were evaluated in 3-time points from day 0 to day 7.

Description

Citation

Jaramillo T., Francisco E. (2024). Polycaprolactone and Polyethylene Terephthalate Nanofiber Grafts for Anterior Cruciate Ligament Tissue Applications. Nazarbayev University School of Engineering and Digital Sciences

Endorsement

Review

Supplemented By

Referenced By

Creative Commons license

Except where otherwised noted, this item's license is described as CC0 1.0 Universal